Shanghai Henlius Biotech Inc.

Gastroesophageal Junction and Gastric Cancer

Clinical development activity includes treatment research in locally advanced and metastatic gastroesophageal junction cancer and gastric cancer, with attention to HER2-directed therapy and combination regimens used in first-line care.

  • HER2-positive gastric malignancies
  • Metastatic gastric cancer
  • Gastroesophageal junction cancer

Research in this area is centered on antibody-based treatment strategies integrated with established chemotherapy backbones and immunotherapy-relevant combinations.

Advanced Non-Small Cell Lung Cancer

The sponsor also funds clinical research in advanced non-small cell lung cancer, with interest in novel oncology biologics evaluated for lung cancer treatment.

  • Advanced NSCLC
  • Lung cancer therapeutics
  • Oncology biologics

This therapeutic area reflects activity in solid-tumor oncology, particularly for patients with advanced disease requiring systemic treatment options.

Monoclonal Antibody and Antibody-Based Oncology

Across its studies, the company shows a clear focus on monoclonal antibody development for cancer, including targeted agents designed for use alongside standard oncology treatments.

  • Recombinant humanized antibodies
  • Targeted cancer therapy
  • Combination antibody regimens

These programs place emphasis on biologic approaches to tumor control in both upper gastrointestinal and thoracic malignancies.

Solid Tumor Clinical Development

The sponsor’s research landscape is concentrated in solid tumor oncology, with active studies spanning multiple countries and sites in Asia and other regions.

  • Metastatic solid tumors
  • Multicenter oncology trials
  • Global cancer development

Its clinical portfolio is focused on cancers with significant unmet need, especially disease settings requiring systemic, targeted, and combination treatment approaches.

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Matched clinical trials

  • A study to evaluate the safety and effectiveness of HLX43 in patients with advanced non-small cell lung cancer

    Recruiting

    2 1 1
    Investigated drugs:
    France Italy Poland Romania Spain
  • Study of HLX22, Trastuzumab, and Chemotherapy for Patients with Advanced or Metastatic Stomach and Gastroesophageal Cancer

    Recruiting

    3 1 1
    Investigated diseases:
    Germany Greece Italy Poland Portugal Romania +1
  • Evaluation of HLX10 Combined with Chemotherapy and Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized, Double-Blind Study

    Not recruiting

    3 1 1
    Investigated diseases:
    Austria Czechia Germany Greece Hungary Latvia +3