Sarcoma Alliance for Research through Collaboration

Soft Tissue Sarcoma

Research activity centers on high-risk soft tissue sarcoma of the extremity, with attention to aggressive localized tumors including undifferentiated pleomorphic sarcoma and dedifferentiated/pleomorphic liposarcoma.

  • Extremity sarcoma
  • Localized high-risk disease
  • Tumors larger than 5 cm
  • Grade 2 or 3 sarcoma

The sponsor’s funded research is directed toward surgical oncology settings where local control and disease recurrence are central clinical concerns.

Radiation Oncology

Clinical interest includes radiotherapy as a key component in the management of localized sarcoma, particularly in the preoperative setting.

  • Neoadjuvant radiotherapy
  • Local tumor control
  • Pre-surgical treatment

This area reflects a focus on integrating radiation-based treatment into multimodal care for extremity sarcoma.

Immuno-Oncology

The sponsor also supports research involving pembrolizumab, highlighting interest in immune-based treatment strategies for sarcoma.

  • Checkpoint inhibition
  • Perioperative immunotherapy
  • Adjuvant treatment

Its research portfolio includes combining immune therapy with local treatment approaches in patients with resectable disease.

Surgical Oncology

Funded studies involve surgical resection as part of curative-intent care for patients with localized extremity sarcoma.

  • Resectable sarcoma
  • Perioperative treatment planning
  • Postoperative disease control

Research in this area is closely tied to treatment sequencing around surgery and recurrence prevention.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Pembrolizumab and Radiotherapy for Patients with High-Risk Soft Tissue Sarcoma in the Limbs

    Recruiting

    2 1 1 1
    Investigated drugs:
    Italy