Rheinische Friedrich-Wilhelms-Universitaet Bonn

Neuroinflammation and acute cerebrovascular injury

Clinical research includes aneurysmal subarachnoid hemorrhage with a focus on inflammatory mechanisms and neurological recovery, alongside studies in glioblastoma that address tumour progression in the central nervous system.

  • Subarachnoid hemorrhage
  • Inflammation in acute brain injury
  • Glioblastoma

These areas reflect sustained interest in neurological disease states where immune modulation and tumour-directed therapy are central clinical concerns.

Oncology and surgical cancer care

The sponsor funds trials in non-small cell lung cancer, ovarian cancer, and malignant extracranial germ cell tumours, with additional attention to perioperative tumour detection and treatment-related outcomes.

  • Non-small cell lung cancer
  • Ovarian cancer
  • Malignant germ cell tumours
  • Intraoperative imaging

Research activity also spans glucocorticoid-sparing strategies and multimodal cancer treatment pathways in advanced solid tumours.

Autoimmune and inflammatory disorders

Several studies address chronic immune-mediated disease, including giant cell arteritis, lichen planus, and radiation-induced oral mucositis, with a strong emphasis on symptom control and disease activity.

  • Giant cell arteritis
  • Lichen planus
  • Oral mucositis
  • Immune system modulation

Related work also includes investigations into innate immune priming and inflammatory responses in healthy subjects.

Metabolic and reproductive health

Research activity covers overweight and obesity-related polycystic ovary syndrome, with attention to menstrual dysfunction and broader endocrine-metabolic disturbance.

  • Polycystic ovary syndrome
  • Ovarian dysfunction
  • Obesity-related endocrine disorders

These trials connect metabolic regulation with reproductive outcomes in women’s health.

Perioperative and pediatric care

The sponsor also supports studies in delayed gastric emptying after pancreatoduodenectomy and pediatric emergence delirium following ENT surgery, reflecting interest in postoperative recovery and anaesthesia-related complications.

  • Pancreatoduodenectomy outcomes
  • Delayed gastric emptying
  • Pediatric emergence delirium
  • Perioperative symptom management

Additional work addresses procedure-related complications and recovery patterns in both adult and paediatric settings.

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Matched clinical trials

  • Study on Nicotine Patch for Preventing Delayed Gastric Emptying in Patients After Pancreatoduodenectomy

    Recruiting

    1 1
    Investigated diseases:
    Investigated drugs:
    Germany
  • Study on the Effects of Dexamethasone in Patients with Aneurysmal Subarachnoid Hemorrhage

    Not recruiting

    1 1 1
    Investigated diseases:
    Germany
  • Study on the Effectiveness of Deucravacitinib for Patients with Lichen Planus

    Not recruiting

    1 1
    Investigated diseases:
    Investigated drugs:
    Germany
  • Study on Methotrexate for Maintaining Remission in Patients with Giant Cell Arteritis After Initial Treatment with Tocilizumab and Glucocorticoids

    Not recruiting

    1 1
    Investigated diseases:
    Investigated drugs:
    Germany
  • Study Comparing Carboplatin and Cisplatin for Patients with Extracranial Malignant Germ Cell Tumors

    Not recruiting

    1 1 1 1
    Austria Germany The Netherlands