Oncology and Haematological Malignancies
Research activity includes treatment strategies for non-small cell lung cancer, triple-negative breast cancer, dedifferentiated liposarcoma, mantle cell lymphoma, diffuse large B-cell lymphoma, gastrointestinal stromal tumor, and neuroendocrine tumours. Additional interest is seen in papillary craniopharyngioma and resectable gastric and gastroesophageal junction adenocarcinoma.
- Solid tumours
- Lymphoma
- Targeted cancer therapy
- Perioperative oncology
Its oncology portfolio spans both tumour-directed therapy and disease-specific management across adult and selected rare cancers.
Neurology and Neurodegenerative Disorders
Clinical research covers Parkinson’s disease, Alzheimer’s disease, frontotemporal dementia, progressive supranuclear palsy, corticobasal degeneration, mild cognitive impairment, traumatic brain injury, subarachnoid hemorrhage, intracerebral hemorrhage, and cerebral commotio.
- Movement disorders
- Dementia and cognitive decline
- Brain injury
- Neuroimaging
There is also interest in tau-related pathology and diagnostic approaches for early neurodegenerative change.
Gastroenterology, Hepatology, and Inflammatory Bowel Disease
Studies address non-alcoholic fatty liver disease, liver tumours, Crohn’s disease, and ulcerative colitis, alongside surgical and medical management of gastrointestinal conditions. The portfolio also includes complement-mediated renal disease such as C3 glomerulopathy.
- Liver disease
- Inflammatory bowel disease
- Renal complement disorders
- Gastrointestinal surgery
Research spans chronic inflammatory disease, metabolic liver disease, and selected hepatobiliary and renal complications.
Cardiovascular, Vascular, and Infectious Diseases
Active areas include abdominal aortic aneurysm, chronic coronary syndrome, infectious endocarditis, Staphylococcus aureus bacteraemia, and urinary tract infection caused by resistant bacteria. The research portfolio also extends to atherosclerotic and vascular intervention topics.
- Vascular surgery
- Coronary disease
- Bacterial bloodstream infection
- Antimicrobial resistance
These studies reflect interest in both procedural outcomes and infection management in complex cardiovascular and surgical settings.
Endocrine, Metabolic, and Mental Health Conditions
Research includes Graves’ ophthalmopathy, Graves’ disease, depression, major depressive disorder, anorexia nervosa, iron deficiency in adolescent girls, and obesity with metabolic liver involvement. The sponsor also funds work in inflammatory rheumatic disease and treatment-related immune responses.
- Thyroid eye disease
- Depressive disorders
- Eating disorders
- Metabolic and nutritional disorders
Its therapeutic interests cover psychiatric care, endocrine autoimmunity, and nutritional deficiency across adolescent and adult populations.
