Breast cancer and geriatric oncology
Research activity includes treatment strategies for advanced breast cancer in older patients, with attention to CDK 4/6 inhibitors, endocrine therapy, and extended adjuvant treatment in high-risk luminal breast cancer. The portfolio also reflects interest in treatment optimisation for vulnerable and frail patients.
- Advanced breast cancer in older patients
- CDK 4/6 inhibitor treatment
- Endocrine therapy sequencing
- High-risk luminal breast cancer
The focus spans both systemic treatment selection and long-term hormonal management in breast oncology.
Cardiology and arrhythmia care
Clinical research covers persistent symptomatic atrial fibrillation, post-operative atrial fibrillation after coronary artery bypass surgery, and myocardial infarction. Interest is evident in catheter ablation, pulmonary vein isolation, antiarrhythmic treatment, and inflammation-related cardiac outcomes.
- Persistent atrial fibrillation
- Post-CABG atrial fibrillation
- Myocardial infarction
- Catheter ablation and pulmonary vein isolation
Additional cardiovascular work includes prevention of rhythm complications and modulation of post-infarction inflammatory responses.
Respiratory medicine and chronic obstructive pulmonary disease
The sponsor supports studies in COPD focused on exacerbation prevention and broader clinical outcomes, including cardiovascular events and mortality. This area links pulmonary disease management with cardiovascular risk in patients without co-existing heart disease.
- Chronic obstructive pulmonary disease
- COPD exacerbations
- Cardiovascular outcomes
- Mortality prevention
The research interest extends to therapies that may influence both respiratory stability and systemic complications.
Psychiatry and immune-based treatment
One research focus is schizophrenia spectrum disorder, with evaluation of rituximab as an immunomodulatory approach for psychotic symptoms. The clinical interest lies in symptom improvement measured through psychiatric response and global clinical status.
- Schizophrenia spectrum disorder
- Psychotic disorder
- Rituximab
- Immunomodulatory therapy
This area reflects involvement in neuropsychiatric treatment strategies beyond conventional antipsychotic care.
Perioperative and paediatric care
Additional studies address pain during eye examination of premature infants and outcomes after total knee arthroplasty and total hip arthroplasty. The perioperative portfolio also includes comparison of general anaesthesia and spinal anaesthesia for same-day discharge, alongside interest in renal and rhythm complications around surgery.
- Retinopathy of prematurity examination pain
- Total knee arthroplasty
- Total hip arthroplasty
- Anaesthesia and postoperative discharge outcomes
The research scope connects paediatric comfort, surgical recovery, and perioperative optimisation.
