Oncology and Molecular Imaging
Radboud universitair medisch centrum Stichting supports research in a broad range of cancer types, including prostate cancer, breast cancer, ovarian cancer, glioblastoma, non-small cell lung cancer, rectal cancer, and renal cell carcinoma. Its portfolio also includes hematologic malignancies such as chronic myeloid leukaemia, myelodysplastic syndromes, and acute myeloid leukemia.
- Prostate cancer and castration-resistant prostate cancer
- Thoracic, gastrointestinal, and urologic malignancies
- Hematologic cancer and cellular immunotherapy
- PET/CT imaging and tumor-targeted diagnostics
The sponsor’s oncology research also extends to precision imaging and immune-based treatment strategies in both solid tumors and blood cancers.
Cardiovascular and Vascular Disease
The sponsor is actively involved in studies of cardiovascular disease, with emphasis on coronary vasospasm, coronary microvascular dysfunction, angina, heart failure, hypertension, peripheral arterial disease, acute myocardial infarction, and aortic valve stenosis.
- Coronary vasomotor disorders
- Aortic valve disease and aortic valve calcification
- Stroke, intracerebral haemorrhage, and subarachnoid hemorrhage
- Antithrombotic therapy and vascular protection
Research in this area also includes blood pressure management, vascular imaging, and treatment approaches for ischemic and hemorrhagic cerebrovascular disease.
Infectious Diseases, Immunology, and Inflammation
Clinical studies cover fungal infection, candidemia, tuberculosis, nontuberculous mycobacterial disease, pertussis, sepsis, and HIV infection, alongside immune-mediated conditions such as systemic sclerosis, Sjögren’s syndrome, primary membranous nephropathy, and inflammatory bowel disease.
- Antifungal and antimicrobial treatment research
- Host immune response and inflammation
- Vaccine immunogenicity and infection prevention
- Autoimmune and immune-mediated renal disease
The sponsor also investigates experimental endotoxemia, immunomodulation, and inflammatory mechanisms linked to acute and chronic disease.
Neurology, Psychiatry, and Pain
Its research portfolio includes Parkinson’s disease, chronic cluster headache, dystonic tremor syndrome, delirium, major depressive disorder, posttraumatic stress disorder, anxiety, fatigue, and GHB use disorder.
- Movement disorders and tremor syndromes
- Mood disorders and trauma-related conditions
- Substance use disorder and detoxification
- Neurological injury and cognitive complications
Additional work addresses stroke recovery, intracerebral bleeding, and symptom control in chronic pain and neurological disease.
Metabolic, Renal, Gastrointestinal, and Endocrine Disorders
The sponsor funds studies in type 1 diabetes, gestational diabetes, diabetic foot ulcer, chronic pancreatitis, predicted severe acute pancreatitis, primary aldosteronism, hypomagnesemia, and primary membranous nephropathy.
- Diabetes-related complications
- Pancreatic inflammation and gastrointestinal disease
- Kidney disease and electrolyte disorders
- Hormonal and metabolic regulation
Research also includes nutrition-related interventions, organ failure prevention, and disease management in complex multisystem conditions.
