Pauls Stradins Clinical University Hospital

Cardiology and Heart Failure

Clinical research includes chronic heart failure with preserved ejection fraction, with attention to symptom control, functional capacity, and exercise-based management. The hospital also studies the role of meldonium alongside individualized physical activity recommendations in this patient group.

  • Heart failure with preserved ejection fraction
  • Physical activity and functional rehabilitation
  • Metabolic support in cardiovascular disease

These studies reflect interest in improving daily performance and clinical stability in patients with chronic cardiac impairment.

Neuro-oncology

Research activity includes glioblastoma, with focus on treatment strategies that may extend survival and support disease control in aggressive brain tumors. The clinical work examines the integration of zoledronic acid with standard cancer therapy.

  • Glioblastoma
  • Oncologic treatment combinations
  • Survival outcomes in malignant brain disease

This area centers on therapeutic options for a high-burden central nervous system malignancy.

Endocrinology and Metabolic Research

The sponsor supports investigation of obesity and related metabolic regulation, including studies of glucagon, energy expenditure, and glucose handling. Research also addresses the interaction between incretin-related pathways and insulin secretion.

  • Obesity
  • Glucagon physiology
  • Glucose metabolism and energy balance

Work in this field is directed toward understanding hormonal control of metabolism and its relevance to weight-related disorders.

Pulmonology and Infectious Disease

Clinical trials also cover simple aspergilloma, with interest in localized antifungal treatment approaches for pulmonary fungal disease. The research includes liposomal Amphotericin B delivered through the bronchial route.

  • Simple pulmonary aspergilloma
  • Fungal lung infection
  • Localized antifungal therapy

This area focuses on management of chronic pulmonary infection within a hospital-based respiratory setting.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Adding Zoledronic Acid to Standard Treatment for Patients with Glioblastoma

    Recruiting

    2 1 1 1
    Investigated diseases:
    Investigated drugs:
    Latvia
  • Study on Meldonium and Physical Activity for Patients with Heart Failure with Preserved Ejection Fraction

    Recruiting

    3 1 1 1
    Investigated drugs:
    Latvia
  • Study to evaluate the efficacy and safety of liposomal amphotericin B for patients with simple pulmonary aspergilloma

    Not yet recruiting

    2 1 1 1
    Investigated drugs:
    Latvia
  • Study of Semaglutide and Glucagon Effects on Energy Expenditure and Glucose Levels in Healthy Volunteers

    Not recruiting

    1 1 1 1
    Investigated diseases:
    Investigated drugs:
    Latvia