Oncology and Hematologic Malignancies
Ospedale San Raffaele S.r.l. is involved in clinical research across several cancer and blood disorder areas, with activity spanning solid tumors and hematologic malignancies. Its studies include chronic lymphocytic leukemia, muscle-invasive bladder cancer, prostate cancer, head and neck cancer, non-small cell lung cancer, and intrahepatic cholangiocarcinoma.
- Chronic lymphocytic leukemia
- Prostate cancer and clinically relevant prostate cancer
- Muscle-invasive bladder cancer
- Head and neck cancer and non-small cell lung cancer
- Intrahepatic cholangiocarcinoma
Research activity also includes biomarker-driven approaches, imaging for tumor detection, and perioperative or combination strategies in oncology.
Neurology and Neuroinflammatory Disease
The sponsor supports studies in multiple sclerosis, including relapsing-remitting and progressive forms, as well as research in migraine and neurodegenerative mechanisms. Additional work addresses Wolfram syndrome type 1, reflecting interest in complex neurological and neurogenetic conditions.
- Relapsing-remitting multiple sclerosis
- Progressive multiple sclerosis
- Migraine
- Wolfram syndrome type 1
- Neurodegenerative phenomena
Its neurological portfolio also touches on immune-mediated pathways and nervous system injury linked to chronic disease.
Cardiovascular and Critical Care Medicine
Clinical research in cardiology and critical care includes conditions such as cardiogenic shock, cardiac arrest, acute respiratory distress syndrome, low-cardiac output syndrome, dilated cardiomyopathy, and myocarditis. The sponsor also studies advanced support settings and postoperative cardiac complications.
- Cardiogenic shock and cardiac arrest
- Acute respiratory distress syndrome
- Low-cardiac output syndrome
- Dilated cardiomyopathy and myocarditis
- Perioperative cardiac support
Work in this area extends to thrombotic and bleeding risk, hemodynamic instability, and cardiopulmonary rescue care.
Autoimmune, Infectious, and Metabolic Disorders
The sponsor’s research covers immune-mediated and systemic diseases including IgG4-related disease, new-onset autoimmune type 1 diabetes, and virus-negative myocarditis. It also includes studies in HIV infection and early treated HIV-1, alongside metabolic and endocrine conditions such as Wolfram syndrome type 1.
- IgG4-related disease
- Autoimmune type 1 diabetes
- Virus-negative myocarditis
- HIV infection and HIV-1
- Metabolic and endocrine syndromes
These studies reflect interest in immune regulation, chronic infection, and autoimmune tissue injury.
Rare Disease, Genetics, and Musculoskeletal Conditions
Ospedale San Raffaele S.r.l. also conducts research in rare genetic diseases and musculoskeletal disorders, including Duchenne muscular dystrophy, Von-Hippel Lindau disease, and arthroscopic anterior cruciate ligament reconstruction. Additional activity includes chronic pelvic pain syndrome and other complex pain-related conditions.
- Duchenne muscular dystrophy
- Von-Hippel Lindau disease
- Anterior cruciate ligament reconstruction
- Chronic pelvic pain syndrome
- Genetic and rare disease research
Its portfolio includes neuromuscular biology, inherited disease mechanisms, and surgical pain management.
