NVALT-studies Stichting

Non-Small Cell Lung Cancer

The research portfolio is centered on completely resected primary stage IB, stage II, and stage IIIA non-small cell lung cancer, with interest in patients whose tumors show PD-L1 expression and lack EGFR and ALK alterations.

  • Adjuvant treatment after complete resection
  • PD-L1–selected lung cancer populations
  • Early-stage and locally advanced disease

Work in this area reflects a focus on postoperative disease control and outcomes in surgically treated lung cancer.

Immuno-Oncology

The sponsor supports research in immune-based cancer therapy for lung malignancy, with attention to treatment strategies intended to reduce recurrence risk after surgery.

  • Checkpoint-directed therapy
  • Tumor immune-marker selection
  • Maintenance of disease-free survival

Its clinical interest lies in evaluating immune-targeted approaches within a defined thoracic oncology setting.

Thoracic Oncology

Clinical activity is concentrated in lung cancer, especially the management of patients following surgical removal of their primary tumor, where recurrence prevention remains a major concern.

  • Resected lung cancer
  • Postoperative oncologic management
  • Localized and regionally advanced disease

This area connects surgical oncology with systemic treatment strategies for non-small cell lung cancer.

Biomarker-Defined Cancer Care

The funded research includes a biomarker-informed approach using PD-L1 status and exclusion of EGFR and ALK alterations to identify a specific treatment population.

  • PD-L1 testing
  • Molecular subtype selection
  • Targeted patient stratification

These interests place emphasis on matching oncology treatment choices to tumor characteristics.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Durvalumab for Patients with Completely Removed Non-Small Cell Lung Cancer

    Not recruiting

    3 1 1
    Investigated diseases:
    Investigated drugs:
    Bulgaria France Hungary Italy The Netherlands Poland +2