National Institute For Infectious Diseases Lazzaro Spallanzani

COVID-19 Immunity and Post-Infection Response

Research activity includes COVID-19 infection and infectious diseases of the respiratory system, with attention to the durability of humoral immunity and cellular immunity after infection and treatment with monoclonal antibodies. The clinical focus also covers the effect of prior vaccination status on immune response.

  • Antibody response
  • T-cell response
  • Revaccination timing

These studies are centered in Rome and reflect ongoing interest in immune recovery after SARS-CoV-2 infection.

COVID-19 Pneumonia and Hospital Care

Another area of interest is hospitalized COVID-19 pneumonia in patients who do not require high oxygen support, including those with and without previous anti-COVID-19 vaccination. The work examines adjunctive therapy alongside standard care in the inpatient setting.

  • Hospitalized patients
  • Respiratory infection management
  • Host-directed therapy

This clinical area aligns with the sponsor’s involvement in acute respiratory infectious disease care.

Pulmonary Tuberculosis

The sponsor also funds research in pulmonary tuberculosis, with particular attention to bacilliferous TB and treatment support alongside standard antitubercular therapy. The therapeutic interest is directed toward improving management of active lung infection.

  • Standard tuberculosis treatment
  • Adjunctive therapy
  • Host-targeted treatment

This area reflects sustained clinical involvement in serious mycobacterial disease.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study of cysteamine combined with standard tuberculosis treatment in adults with pulmonary tuberculosis

    Recruiting

    1 1 1
    Investigated diseases:
    Investigated drugs:
    Italy
  • Study on Immune Response in COVID-19 Recovered Patients Treated with Monoclonal Antibodies: Effects of Revaccination with Elasomeran, Tozinameran, and Cilgavimab

    Not yet recruiting

    1 1 1 1
    Italy
  • Study on the Safety of Mercaptamine with Standard Therapy for Hospitalized COVID-19 Pneumonia Patients Not Requiring High Oxygen Flows

    Not yet recruiting

    1 1 1
    Investigated drugs:
    Italy