Narodowy Instytut Onkologii Im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy

Hematologic malignancies

The sponsor is active in clinical research for acute myeloid leukemia, acute lymphoblastic leukemia, and myelodysplastic syndromes, with interest in treatment strategies used before transplantation and in newly diagnosed disease.

  • Acute myeloid leukemia
  • Acute lymphoblastic leukemia
  • Myelodysplastic syndromes

Its research also includes hematopoietic cell transplantation and remission-focused outcomes in adult blood cancers.

Solid tumors of the head, neck, and skin

Clinical activity covers head and neck squamous cell carcinoma, nasopharyngeal cancer, and advanced non-melanoma skin cancers, including difficult-to-treat squamous and basal cell subtypes.

  • Head and neck squamous cell carcinoma
  • Nasopharyngeal cancer
  • Advanced non-melanoma skin cancer

Research interests include immunotherapy, radiotherapy, and treatment approaches for unresectable or progressive disease.

Sarcomas and rare solid tumors

The sponsor funds studies in soft tissue sarcomas, gastrointestinal stromal tumors, adenoid cystic carcinoma, and adrenocortical carcinoma, reflecting a strong focus on rare and high-risk malignancies.

  • Soft tissue sarcomas
  • Gastrointestinal stromal tumors
  • Adenoid cystic carcinoma
  • Adrenocortical carcinoma

There is also interest in metastatic disease, resectable tumors, and adjuvant or preoperative treatment settings.

Breast, prostate, and genitourinary oncology

Research extends to HER2-negative breast cancer and prostate cancer, including patients with locally advanced, recurrent, or metastatic disease.

  • HER2-negative breast cancer
  • Prostate cancer
  • Genitourinary oncology

These studies include interest in radiotherapy, hormone therapy, and disease control after radical treatment.

The sponsor also investigates conditions linked to cancer care, including cardiotoxicity, chronic kidney disease, and nicotine dependence in patients with oncologic comorbidity.

  • Cardiotoxicity
  • Chronic kidney disease
  • Nicotine dependence

Additional interest is shown in protecting cardiac function during anthracycline-based treatment and in managing supportive care needs alongside cancer therapy.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Preoperative Treatment for HER2-Negative Breast Cancer Using Pembrolizumab, Paclitaxel, and Carboplatin in Patients Not Responding to Initial Chemotherapy

    Recruiting

    1 1 1
    Investigated diseases:
    Poland
  • Study of Avelumab and Axitinib for Patients with Unresectable or Metastatic Gastrointestinal Stromal Tumors After Standard Therapy Failure

    Not recruiting

    1 1 1
    Investigated drugs:
    Italy Poland
  • Study of L-Annamycin Treatment for Patients with Previously Treated Metastatic Soft Tissue Sarcoma

    Not recruiting

    1 1
    Investigated diseases:
    Investigated drugs:
    Poland
  • Study of Pembrolizumab for Patients with Advanced Adrenocortical Carcinoma

    Not recruiting

    1 1 1
    Investigated diseases:
    Investigated drugs:
    Poland
  • Study on Obinutuzumab and Rituximab with Chemotherapy for Adults with Newly Diagnosed CD20-Positive Acute Lymphoblastic Leukemia

    Not recruiting

    1 1 1
    Investigated drugs:
    Poland
  • Study on Pembrolizumab and Eftilagimod Alfa with Radiotherapy for Patients with Resectable Soft Tissue Sarcomas

    Not recruiting

    1 1 1
    Poland