Rare Metabolic Disorders
Research activity includes propionic acidemia, isolated methylmalonic acidemia due to methylmalonyl-CoA mutase deficiency, methylmalonic acidemia, phenylketonuria, and glycogen storage disease type 1a, with a focus on inherited conditions affecting metabolic function.
- Propionic acidemia
- Isolated methylmalonic acidemia
- Phenylketonuria
- Glycogen storage disease type 1a
These studies reflect interest in disorders with early onset, recurrent metabolic decompensation, and long-term disease burden.
Respiratory Viral Vaccines
The sponsor is active in influenza, respiratory syncytial virus, SARS-CoV-2 infection, and acute lower respiratory infection, supporting vaccine research across seasonal and pandemic respiratory threats.
- Influenza
- Respiratory syncytial virus
- SARS-CoV-2 infection
- Acute lower respiratory infection
Clinical interest spans adult protection, prevention of medically attended illness, and coverage across changing respiratory virus strains.
Maternal and Infant Immunization
Research also extends to pregnancy and early-life protection, with studies involving maternal vaccination and infant safety assessments for cytomegalovirus infection prevention.
- Pregnancy
- Infant safety
- Cytomegalovirus infection
- Maternal immunization
This area includes immune protection during gestation and disease prevention in newborns and young infants.
Long-term Safety and Ongoing Disease Management
Several trials focus on long-term safety, tolerability, and continued clinical follow-up in chronic diseases, including metabolic and infectious conditions.
- Long-term safety
- Tolerability
- Chronic disease follow-up
- Clinical activity
These studies cover repeat observation in participants previously enrolled in earlier research programs and sustained assessment of treatment-related outcomes.
