Haematology and Leukaemia
Research activity includes acute myeloid leukaemia with IDH1-mutated AML, myelodysplastic syndrome, and relapsed or refractory AML, alongside chronic lymphocytic leukaemia and small lymphocytic lymphoma. The portfolio also covers minimal residual disease assessment in AML and CLL.
- Acute myeloid leukaemia
- Myelodysplastic syndrome
- Chronic lymphocytic leukaemia
- Minimal residual disease
Clinical interest extends to treatment-resistant disease, remission status, and consolidation strategies in blood cancers.
Oncology and Cancer Prevention
Trials address Li-Fraumeni syndrome and cancer surveillance in individuals at elevated hereditary risk, with attention to metformin in cancer prevention. The research profile also includes therapeutic approaches linked to malignancy control in haematologic and genetic cancer predisposition settings.
- Li-Fraumeni syndrome
- Cancer surveillance
- Metformin
- Hereditary cancer risk
These studies connect inherited cancer susceptibility with preventive oncology and long-term risk management.
Nephrology
Research includes autosomal dominant polycystic kidney disease, with interest in kidney growth and disease modification. The focus reflects active work in inherited renal disorders and chronic kidney disease-related outcomes.
- Autosomal dominant polycystic kidney disease
- Kidney growth
- Inherited renal disease
The renal portfolio is centred on progression-related endpoints and therapeutic options for genetic kidney disease.
Cardiovascular Medicine and Lipid Management
Clinical work includes coronary artery disease and myocardial infarction, with studies targeting LDL cholesterol control in patients not reaching guideline goals. The research also covers treatment intensification for acute coronary syndrome and related cardiovascular risk reduction.
- Coronary artery disease
- Myocardial infarction
- LDL cholesterol
- Acute coronary syndrome
Therapeutic interest is directed toward lipid-lowering strategies and secondary prevention in cardiovascular disease.
Hepatology and Otolaryngology
Additional studies address chronic hepatitis B and immune-based treatment concepts, as well as hearing loss and cochlear implantation with intraoperative or adjuvant interventions. These areas broaden the sponsor’s research coverage across infectious disease and sensory disorders.
- Chronic hepatitis B
- Hepatitis B immunoglobulins
- Hearing loss
- Cochlear implantation
Work in these fields includes antiviral management and surgical adjuncts for auditory rehabilitation.
