Hematologic malignancies
Research activity includes acute myeloid leukaemia and acute lymphoblastic leukemia, with interest in molecularly guided treatment, FLT3-mutated AML, CBF-AML, and JAK/STAT pathway-driven disease.
- Acute myeloid leukaemia
- Acute lymphoblastic leukemia
- Targeted leukemia therapy
- Personalized oncology
The sponsor’s oncology portfolio also reflects interest in combination treatment strategies for paediatric and adult leukaemia care.
Autoimmune and inflammatory disorders
Clinical research covers ulcerative colitis and atopic dermatitis, with focus on biologic therapy, immunosuppression, and treatment options for moderate to severe immune-mediated disease.
- Ulcerative colitis
- Atopic dermatitis
- Biologic therapy
- Immune-mediated inflammation
These studies include comparative work on monotherapy and combined regimens in both adult and paediatric populations.
Nephrology and rare diseases
Funding interests include idiopathic steroid-sensitive nephrotic syndrome and Fabry disease, with attention to podocytopathies, cardiac involvement, and disease recurrence.
- Idiopathic steroid-sensitive nephrotic syndrome
- Fabry disease
- Podocytopathy
- Cardiomyopathy
Research activity in this area also includes enzyme replacement therapy and chaperone therapy-related clinical questions.
Neurology and cognitive disorders
The sponsor supports studies in Alzheimer’s disease and mild cognitive impairment, with emphasis on cognitive function, memory, attention, and daily living outcomes.
- Alzheimer’s disease
- Mild cognitive impairment
- Neurocognitive decline
- Dementia-related care
Its research interests extend to interventions aimed at brain atrophy and functional connectivity in neurodegenerative disease.
Metabolic and paediatric chronic disease
Additional clinical interests include type 1 diabetes, attention-deficit hyperactivity disorder, and heterozygous familial hypercholesterolemia, with a clear paediatric focus across several studies.
- Type 1 diabetes
- Attention-deficit hyperactivity disorder
- Heterozygous familial hypercholesterolemia
- Paediatric medicine
Research in this domain includes cardiometabolic risk reduction, behavioural health, and long-term management of chronic disease in children and adolescents.
