Neurocritical Care and Cerebrovascular Disease
Clinical research includes aneurysmal subarachnoid hemorrhage, with interest in interventions aimed at improving neurological outcome and preventing secondary brain injury.
- Subarachnoid hemorrhage
- Intracranial vascular injury
- Neuroprotection
The sponsor’s work in this area centers on acute brain injury and recovery after hemorrhagic events.
Haematology, Oncology, and Cellular Therapy
Research activity covers newly diagnosed acute myeloid leukemia, primary diffuse large B-cell lymphoma of the central nervous system, advanced-stage malignancies with BRAF mutations, and recurrent prostate cancer.
- Acute myeloid leukemia
- Central nervous system lymphoma
- Targeted oncology
Additional interest extends to immunotherapy combinations and treatment strategies for cancers with limited standard options.
Transplantation and Graft-versus-Host Disease
The sponsor studies steroid-refractory chronic graft-versus-host disease, steroid-refractory overlap syndrome graft-versus-host disease, and immune complications after allogeneic stem cell transplantation.
- Chronic graft-versus-host disease
- Overlap syndrome GVHD
- Post-transplant immune dysfunction
Related work includes management of immune-related adverse events associated with checkpoint inhibitor therapy.
Viral Infections and Post-Transplant Immunology
Clinical trials address CMV, EBV, and adenovirus infections in patients after haematopoietic stem cell transplantation, particularly when standard antiviral treatment is insufficient.
- Cytomegalovirus infection
- Epstein-Barr virus infection
- Adenoviral infection
This area reflects a strong focus on difficult-to-treat opportunistic infections in immunocompromised patients.
Ophthalmology and Refractive Error
Research also includes progressive myopia in children, with attention to strategies for slowing myopia progression.
- Paediatric myopia
- Refraction control
- Ocular growth
The sponsor’s portfolio in this field is focused on early intervention in childhood vision disorders.
