KRKA tovarna zdravil d.d. Novo mesto

Arterial Hypertension

Research activity in arterial hypertension centers on blood pressure control with single-pill combinations containing telmisartan, amlodipine, and hydrochlorothiazide. The clinical focus includes sustained 24-hour pressure reduction and office blood pressure management in adults with grade 1, grade 2, and grade 3 hypertension.

  • Telmisartan/amlodipine
  • Telmisartan/amlodipine/hydrochlorothiazide
  • 24-hour blood pressure reduction
  • Blood pressure variability

The therapeutic interest extends to combination treatment strategies used in cardiovascular risk management.

Hyperlipidaemia

Studies in hyperlipidaemia examine LDL cholesterol lowering in patients with high or very high cardiovascular risk. The research includes rosuvastatin and rosuvastatin/ezetimibe combinations, with attention to achieving guideline-based lipid targets.

  • Rosuvastatin
  • Rosuvastatin/ezetimibe
  • LDL-C goal achievement
  • Cardiovascular risk reduction

The lipid-focused portfolio reflects interest in therapies for patients requiring intensive cholesterol management.

Knee Osteoarthritis

Research in knee osteoarthritis addresses pain-related and inflammatory aspects of the condition, with attention to synovial fluid biomarkers such as interleukin-6. The therapeutic area includes naproxen sodium and its effects on joint inflammation and clinical symptoms.

  • Naproxen sodium
  • Synovial fluid cytokines
  • Interleukin-6
  • Clinical outcomes in osteoarthritis

This area combines interest in musculoskeletal pain with inflammatory mechanisms relevant to joint disease.

Cardiovascular and Metabolic Therapy

The sponsor’s clinical research landscape is strongly oriented toward cardiovascular medicine and metabolic disease management, particularly therapies used to control blood pressure and lipid disorders. These areas reflect a focus on chronic conditions that require long-term pharmacological treatment.

  • Antihypertensive combinations
  • Lipid-lowering therapy
  • Cardiovascular disease risk
  • Chronic disease management

The funded trials also involve multicentre collaboration across several countries and research sites in Europe.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Lowering Cholesterol with Rosuvastatin or Rosuvastatin/Ezetimibe in Patients at High or Very High Risk of Cardiovascular Disease with High Cholesterol

    Not recruiting

    1 1 1 1
    Investigated diseases:
    Investigated drugs:
    Croatia Germany Hungary Poland Slovenia
  • Study on the Effects of Telmisartan, Amlodipine, and Hydrochlorothiazide on Blood Pressure in Patients with Hypertension

    Not recruiting

    1 1 1 1
    Hungary Poland Slovenia
  • Study on Naproxen Sodium and Paracetamol for Patients with Knee Osteoarthritis

    Not recruiting

    1 1 1
    Poland