Katholisches Klinikum Bochum gGmbH

Diabetes and Postprandial Glycaemic Control

The sponsor’s clinical research includes Type 1 diabetes, with attention to post-meal blood glucose regulation, rapid-acting mealtime insulin, and the metabolic consequences of hyperglycaemia.

  • Postprandial glucose profiles
  • Rapid-acting insulin therapy
  • Oxidative stress

Interest in this area centres on matching insulin action to gastric emptying and improving metabolic stability after meals.

Heart Failure and Cardiometabolic Disease

Another area of activity is heart failure with preserved ejection fraction (HFpEF), including cases with or without metabolic dysfunction-associated steatotic liver disease (MASLD), reflecting a focus on intertwined cardiac and metabolic conditions.

  • HFpEF
  • MASLD
  • Cardiometabolic disorders

The research landscape addresses how metabolic abnormalities intersect with heart failure symptoms and functional limitation.

Metabolic Regulation and Glucagon Biology

Work funded by the sponsor also examines glucagon in relation to metabolism, with interest in its effects on energy balance and related physiological responses in HFpEF.

  • Glucagon
  • Metabolic effects
  • Energy utilisation

This domain links endocrine regulation to broader cardiometabolic function.

Physical Performance and Exercise Capacity

The sponsor shows interest in physical performance outcomes, including exercise tolerance and VO2max, particularly in patients with HFpEF and associated metabolic disease.

  • VO2max
  • Exercise capacity
  • Functional status

These studies connect cardiovascular symptoms with measurable limitations in daily physical activity.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study of glucagon effects on physical capacity in patients with heart failure with preserved ejection fraction (HFpEF) with or without liver steatosis

    Recruiting

    2 1 1
    Germany
  • Study on Insulin Lispro and Insulin Human for Managing Blood Sugar After Meals in Type 1 Diabetes Patients with Different Gastric Emptying Rates

    Not recruiting

    1 1 1 1
    Investigated diseases:
    Germany