Emergency medicine and acute resuscitation
The clinical research activity is centered on haemorrhagic shock in the emergency room, with interest in rapid volume replacement and early haemodynamic support.
- Haemorrhagic shock
- Emergency department care
- Hemodynamic stabilization
The focus is on interventions used during immediate trauma resuscitation and the restoration of circulatory function in critically unstable patients.
Blood product therapy and plasma replacement
Research interest includes the early use of lyophilized plasma as an alternative to conventional crystalloid infusion in patients with acute blood loss.
- Lyophilized plasma
- Plasma-based resuscitation
- Volume replacement therapy
This area reflects a therapeutic emphasis on restoring circulating volume through blood-derived products in urgent care settings.
Endothelial protection and circulatory support
The funded research also addresses the role of plasma therapy in supporting the endothelium and maintaining vascular integrity during shock states.
- Endothelial function
- Vascular integrity
- Fluid balance
Interest extends to reducing dependence on large volumes of crystalloid fluids in order to limit volume overload in acute care.
Lactate normalization and metabolic recovery
Clinical outcomes in the supported trial include recovery markers linked to perfusion, with particular attention to lactate levels as an indicator of improved tissue oxygenation.
- Lactate clearance
- Tissue perfusion
- Metabolic stabilization
This reflects a therapeutic interest in monitoring early physiologic response after resuscitative treatment in severe bleeding emergencies.
