Oncology
Clinical research in localised colon cancer focuses on adjuvant treatment strategies, circulating tumor DNA as a biomarker of response, and comparisons between intensified and conventional chemotherapy approaches.
- Colon cancer
- Adjuvant chemotherapy
- Circulating tumor DNA
The oncology portfolio centres on treatment optimisation in stage II-III colorectal cancer.
Cardiovascular Medicine
Research activity includes acute coronary syndrome and refractory heart failure, with interest in symptom burden, functional outcomes, and therapies that support fluid and sodium balance in complex cardiac disease.
- Acute coronary syndrome
- Refractory heart failure
- Intravenous iron
Studies also address quality of life in older adults with post-acute cardiac conditions.
Nephrology and Electrolyte Disorders
The sponsor funds trials in chronic kidney disease and hyperkalemia, including management of potassium imbalance and preservation of RAASi and MRA therapy in patients with renal impairment.
- Chronic kidney disease
- Hyperkalemia
- Sodium zirconium cyclosilicate
Additional work explores natriuresis and peritoneal sodium elimination in people receiving peritoneal dialysis.
Endocrinology and Metabolic Disease
Clinical studies in type 2 diabetes mellitus examine pharmacogenetic-guided treatment and personalised approaches for patients with insufficient glycaemic control.
- Type 2 diabetes mellitus
- Pharmacogenetics
- Personalised treatment
The diabetes programme is centred on improving treatment selection through genetic information.
Orthopaedic Surgery and Perioperative Care
Research in hip fracture addresses perioperative haemodynamic stability and anaesthetic choice in older adults undergoing surgery, with attention to arterial pressure, oxygen saturation, and heart rate.
- Hip fracture surgery
- Subarachnoid anesthesia
- Hemodynamic safety
This area reflects a focus on surgical care for older patients with fragility fractures.
