Idorsia Pharmaceuticals Ltd.

Sleep Medicine and Sleep Disorders

Research activity includes insomnia disorder, with attention to sleep maintenance and daytime functioning in people affected by persistent sleep disruption. The portfolio also includes sleep-related studies in pediatric and adolescent populations, as well as cases where insomnia occurs alongside nocturia.

  • Insomnia disorder
  • Comorbid nocturia
  • Pediatric sleep disturbance
  • Objective sleep assessment

The therapeutic focus extends across adult and younger age groups, reflecting interest in sleep regulation and related quality-of-life burdens.

Neurology and Neuroinflammation

Clinical research covers progressive multiple sclerosis, with emphasis on central nervous system repair and disease-related neurological impairment. This area also includes interest in remyelination and brain imaging markers relevant to neurodegenerative change.

  • Progressive multiple sclerosis
  • Remyelination
  • Magnetic resonance imaging
  • Neurological disability

The research portfolio reflects a strong neurological interest in conditions where preserving or restoring nerve function is clinically important.

Dermatology and Inflammatory Skin Disease

Studies in moderate to severe chronic plaque psoriasis show a clear commitment to immune-mediated skin disease. The research addresses persistent inflammatory burden, visible skin involvement, and the broader impact of psoriasis on daily life, including cases with psoriatic arthritis.

  • Chronic plaque psoriasis
  • Psoriatic arthritis
  • Inflammatory dermatoses
  • Skin disease severity

This area centers on immune-driven dermatologic conditions requiring ongoing therapeutic management.

Rare Disease and Metabolic Disorders

Research includes Fabry disease, a hereditary lysosomal storage disorder with systemic manifestations. The sponsor’s interests also extend to long-term treatment evaluation in rare metabolic disease settings where chronic disease control and tolerability are key concerns.

  • Fabry disease
  • Lysosomal storage disorder
  • Metabolic disease
  • Long-term safety

This therapeutic domain reflects engagement with inherited conditions that affect multiple organ systems.

Infectious Disease and Healthy Volunteer Research

The portfolio also includes work related to Clostridioides difficile, alongside studies in healthy volunteers that support evaluation of medicine behavior in controlled settings. These activities indicate interest in both infectious disease and foundational clinical research populations.

  • Clostridioides difficile
  • Healthy volunteer studies
  • Drug interaction assessment
  • Women’s health

Additional work touches on reproductive and pharmacological considerations relevant to everyday clinical use.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • A study testing ACT-1004-1239 compared to placebo for adults with progressive multiple sclerosis to measure nerve repair using MRI scans

    Recruiting

    2 1
    Investigated diseases:
    Investigated drugs:
    The Netherlands
  • Testing IDOR-1117-2520 for Adults with Moderate to Severe Chronic Plaque Psoriasis With or Without Psoriatic Arthritis

    Not recruiting

    2 1
    Investigated diseases:
    Investigated drugs:
    Bulgaria Romania
  • Study to Determine Safe and Effective Dose of Daridorexant for Treating Insomnia in Children and Adolescents Aged 10 to 18 Years

    Not recruiting

    2 1 1
    Investigated drugs:
    Bulgaria Germany Italy Spain
  • Study on Long-Term Safety of Oral Lucerastat for Adults with Fabry Disease

    Not recruiting

    3 1 1
    Investigated diseases:
    Investigated drugs:
    Austria Belgium France Germany Norway Poland +1
  • Study on Daridorexant for Treating Insomnia in Patients with Insomnia and Nocturia

    Not recruiting

    3 1 1
    Investigated diseases:
    Investigated drugs:
    Germany Spain