Maternal-fetal medicine and obstetric care
Clinical research at Hospital Universitario 12 De Octubre includes management of fetal growth restriction in late pregnancy, with attention to labor induction, cervical ripening, and delivery outcomes in term pregnancies.
- Intrauterine growth restriction
- Vaginal delivery
- Neonatal morbidity
The sponsor’s obstetric research is centered in Madrid and reflects active clinical interest in improving perinatal care for pregnancies complicated by impaired fetal growth.
Addiction medicine and substance use disorder
The hospital also funds studies in alcohol dependence, focusing on treatment-oriented outcomes such as changes in alcohol consumption and biochemical markers used to monitor abstinence in patients seeking care.
- Alcohol abstinence
- Alcohol consumption assessment
- Biomarker monitoring
This area highlights interest in clinical approaches for individuals with substance use disorders who are engaged in treatment services.
Rare disease and neurometabolic disorders
Another therapeutic focus is thymidine kinase 2 deficiency, a rare condition associated with mitochondrial disease and muscle weakness, with research directed toward adult patients affected by this inherited disorder.
- TK2 deficiency
- Mitochondrial dysfunction
- Adult rare disease care
These studies place the sponsor within the field of orphan disease research, with attention to conditions that require highly specialized clinical management.
Clinical therapeutics and supportive treatment research
The trial portfolio includes evaluation of cannabidiol in alcohol dependence and investigation of doxecitine and doxribtimine in TK2 deficiency, showing interest in therapeutic options across both psychiatric and rare metabolic conditions.
- Cannabidiol
- Rare disease therapeutics
- Metabolic treatment innovation
Research activity spans obstetrics, addiction medicine, and genetic metabolic disease, with all active trials currently concentrated in Spain.



