Cardiology and Heart Failure
Research activity is centred on chronic heart failure across NYHA class I-III, with particular attention to treatment optimisation in older patients and those at elevated risk of hyperkalaemia.
- Chronic heart failure
- Older adults with cardiac disease
- Hyperkalaemia-associated cardiovascular care
The clinical focus includes strategies that support continued use of guideline-directed heart failure therapy in patients whose electrolyte profile may limit treatment options.
Nephrology and Chronic Kidney Disease
The sponsor’s research landscape includes non-dialysis chronic kidney disease, reflecting interest in patients with combined cardiac and renal disease who require coordinated management.
- Chronic kidney disease
- Non-dialysis renal impairment
- Cardiorenal syndrome
Attention is directed toward preserving renal and cardiovascular treatment pathways in patients with overlapping cardiorenal risk.
Renin-Angiotensin-Aldosterone System Therapy
Clinical interest extends to optimisation of RAASi use, with emphasis on achieving and maintaining recommended treatment targets in patients with heart failure and CKD.
- RAASi optimisation
- Guideline-directed therapy
- Target-dose implementation
This area reflects a focus on sustaining evidence-based cardiovascular and renal therapies when treatment tolerance is constrained by potassium imbalance.
Electrolyte Management and Potassium Binders
The sponsor is involved in research on management of elevated serum potassium, including the role of potassium binders in supporting ongoing RAASi therapy.
- Hyperkalaemia management
- Potassium binders
- Serum potassium control
These studies align with the clinical need to balance electrolyte control and continuation of therapies important for cardiovascular and renal care.
Geriatric Multimorbidity
Research activity also addresses the care of elderly patients living with multiple chronic conditions, especially the coexistence of heart failure, kidney disease, and hyperkalaemia.
- Elderly patient care
- Multimorbidity
- Cardiorenal comorbidity
The clinical emphasis is on treatment choices relevant to patients whose combined cardiac and renal conditions require careful therapeutic coordination.
