Neurodegenerative Disorders
Clinical research at Helse Fonna HF is centered on dementia with Lewy bodies, with attention to the cognitive, neuropsychiatric, and functional features of the condition. The sponsor’s current trial activity is focused on patients in the early stages of the disease.
- Dementia with Lewy bodies
- Cognitive impairment
- Neuropsychiatric symptoms
- Functional decline
The research portfolio reflects interest in clinical outcomes relevant to diagnosis and symptom burden in Lewy body dementia.
Cognitive Assessment
The sponsor’s trial activity includes evaluation of cognitive function using standardized measures in participants with prodromal and mild disease. This area highlights interest in changes in memory, attention, and overall mental performance.
- Mini-Mental State Examination
- Cognitive performance
- Early-stage dementia
Research in this domain is aimed at understanding measurable cognitive effects in people affected by Dementia with Lewy Bodies.
Neuropsychiatry
Helse Fonna HF is involved in research addressing the neuropsychiatric aspects of Lewy body dementia, including symptoms that influence behavior, perception, and daily functioning. The clinical focus extends beyond cognition to the broader psychiatric presentation of the disorder.
- Psychiatric symptoms
- Behavioral changes
- Perceptual disturbances
This area supports clinical interest in symptom patterns that are characteristic of Dementia with Lewy Bodies.
Therapeutic Evaluation
The sponsor’s research includes assessment of ambroxol in relation to clinical outcomes in Dementia with Lewy bodies. The therapeutic focus is on determining whether treatment is associated with improvements in cognition, symptoms, and everyday function.
- Ambroxol
- Clinical efficacy
- Functional outcomes
Current activity is concentrated in a multicentre setting with collaboration across several research sites in Norway.
