Hematologic Malignancies and Transplantation
Research activity includes myelodysplastic syndrome, chronic myelomonocytic leukemia, and secondary acute myeloid leukemia in the setting of allogeneic stem cell transplantation, with attention to conditioning strategies and post-transplant disease control.
- High-risk MDS
- CMML
- sAML
- Venetoclax
- FLAMSA-based conditioning
The clinical focus centers on transplant-related treatment for aggressive myeloid neoplasms and supportive approaches for patients proceeding to blood stem cell transplantation.
Biliary Tract Cancers
The sponsor is involved in studies of cholangiocarcinoma and gallbladder carcinoma after prior gemcitabine treatment failure, reflecting an interest in advanced hepatobiliary oncology.
- Advanced cholangio- and gallbladder carcinoma
- Second-line treatment
- Trifluridine/tipiracil
- Nanoliposomal irinotecan
- Metastatic disease
These trials address difficult-to-treat biliary tract malignancies with a focus on systemic therapy options for progressive disease.
Neuro-Oncology
Clinical research also covers newly diagnosed glioblastoma, with interest in integrating dendritic cell vaccination into standard treatment pathways that include surgery, radiotherapy, and temozolomide.
- Newly diagnosed glioblastoma
- Dendritic cell vaccines
- Temozolomide-based therapy
- Resection and radiotherapy
- Immunotherapy in brain tumors
This area reflects a therapeutic interest in brain tumor immunotherapy alongside established multimodal management of glioblastoma multiforme.
