Autoimmune Kidney Disease
Clinical research includes anti-GBM antibody disease (Goodpasture disease), with interest in severe glomerular injury and immune-mediated loss of kidney function.
- Anti-GBM antibody disease
- Goodpasture disease
- Kidney function
The therapeutic focus in this area is on conditions where pathogenic antibodies drive rapid renal damage.
Kidney Transplant Desensitisation
Research activity also centres on highly sensitised patients awaiting kidney transplantation, including those with a positive crossmatch against a potential donor.
- Highly sensitised patients
- Crossmatch conversion
- Kidney transplant list
This area reflects a strong therapeutic interest in enabling transplantation for patients with limited donor compatibility.
Paediatric Transplant Medicine
The sponsor funds studies in highly sensitised paediatric patients with donor-specific antibodies affecting access to transplantation.
- Paediatric kidney transplantation
- Living donor
- Deceased donor
These trials place emphasis on transplant access in children with complex immunological barriers.
Graft Survival and Long-Term Transplant Outcomes
Additional research addresses graft failure-free survival after imlifidase administration in kidney transplant recipients, including follow-up in previously treated cohorts.
- Graft failure-free survival
- Imlifidase
- Post-transplant follow-up
Studies in this domain are focused on transplant durability and outcomes in patients with challenging immunological profiles.
