Oncology imaging
Research activity includes positron emission tomography and computed tomography applications in metastatic breast cancer, colorectal cancer, gastric cancer, ovarian cancer, pancreatic cancer, and head and neck squamous cell carcinoma. The portfolio also covers imaging of peritoneal carcinomatosis and other advanced solid tumours.
- FES PET/CT
- HER2 imaging
- 68Ga PET/CT
- Peritoneal carcinomatosis detection
Clinical interest extends to imaging biomarkers that support treatment selection and disease characterisation in advanced cancer.
Breast cancer receptor imaging
Trials focus on molecular imaging of oestrogen receptor expression and HER2 status in metastatic breast cancer, with attention to cases that relapse after prior hormone-based treatment. The research also includes visualisation of receptor-targeted disease patterns using specialised PET tracers.
- ER-positive disease
- HER2-negative disease
- Receptor-targeted PET imaging
This area supports imaging approaches for identifying biologically distinct breast cancer subtypes.
Paediatric and cardiovascular imaging
Research includes cardiac perfusion imaging in paediatric patients and evaluation of imaging agents used in radionuclide myocardial perfusion imaging. The cardiovascular work also relates to assessment of children being investigated for Kawasaki disease, congenital heart disease, congenital coronary abnormalities, and post-surgical or post-transplant cardiac conditions.
- Stress perfusion CMR
- Myocardial blood flow assessment
- Paediatric cardiology
The portfolio includes imaging tools used to evaluate cardiac function and perfusion across childhood and adolescence.
Hepatobiliary and abdominal ultrasound
Work in this area centres on contrast-enhanced ultrasound for characterising focal liver lesions, including differentiation between benign and malignant findings in paediatric patients. The studies also address abdominal imaging needs in oncology, particularly for liver and peritoneal disease evaluation.
- Contrast-enhanced ultrasound
- Focal liver lesion characterisation
- Paediatric liver imaging
Imaging development in this field supports improved anatomical and lesion-specific assessment in liver-related disease.
Healthy volunteer imaging and safety evaluation
Clinical research also includes studies in healthy volunteers to assess imaging agents and their use in magnetic resonance imaging and PET/CT. This area covers evaluation of cardiac safety, tolerability, and imaging performance for diagnostic applications.
- Healthy volunteer studies
- MRI contrast imaging
- Cardiac safety assessment
The research supports development of imaging agents for diagnostic use across oncology, cardiovascular, and general imaging settings.
