Fundacion Publica Para La Investigacion Biosanitaria De Andalucia Oriental Alejandro Otero

Ocular Surface Disease

Clinical research in corneal ulcer focuses on severe, treatment-resistant lesions of the eye surface and the restoration of the trophic defect. The sponsor’s activity in this area is centered on regenerative approaches for damaged corneal tissue.

  • Severe corneal ulcer
  • Corneal regeneration
  • Ocular surface repair

Research in this field reflects interest in therapies for persistent epithelial injury and structural recovery of the cornea.

Cleft Lip and Palate

Another major area of interest is cleft palate, with studies addressing reconstruction of oral tissues and support for anatomic restoration in congenital craniofacial conditions. The work includes palatal mucosa replacement strategies.

  • Cleft palate repair
  • Oral mucosa substitute
  • Craniofacial reconstruction

This research area is linked to tissue replacement approaches for defects affecting the palate and surrounding oral structures.

Tissue Engineering

The sponsor funds work involving tissue-engineered constructs designed to replace or support damaged human mucosal tissue. These studies emphasize the use of autologous materials in reconstructive care.

  • Autologous tissue engineering
  • Nanostructured fibrin-agarose scaffold
  • Mucosal reconstruction

Research in this domain connects regenerative medicine with surgical restoration of oral and ocular tissues.

Regenerative Medicine

Clinical activity also extends to regenerative medicine applications aimed at replacing injured tissue and promoting repair in epithelial and mucosal disorders. The sponsor’s funded trials explore biologically derived substitutes for structural recovery.

  • Human tissue substitute
  • Epithelial repair
  • Biomaterial-based reconstruction

These interests place emphasis on restoring function in localized defects of the eye and oral cavity.

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Matched clinical trials

  • Study on the Effectiveness of NANOULCOR for Patients with Severe Corneal Ulcers Using Allogenic Limbal Cells and Keratocytes

    Recruiting

    2 1 1
    Spain
  • Study on the Safety and Feasibility of Using Autologous Oral Mucosa-Derived Keratinocytes and Fibroblasts for Treating Cleft Palate Patients

    Recruiting

    2 1 1
    Spain