Cardiac inflammation and myocardial injury
Research activity includes acute myocarditis, with attention to cardiac magnetic resonance findings, left ventricular function, and inflammatory injury in the setting of preserved systolic performance.
- Acute myocarditis
- Myocardial inflammation
- Cardiac imaging
Interest extends to clinical questions in non-steroidal anti-inflammatory drugs and standard analgesic care for myocardial inflammation.
Inherited and infiltrative cardiomyopathy
The sponsor funds studies in transthyretin cardiac amyloidosis and in genetic carriers of dilated cardiomyopathy, focusing on early cardiac remodeling, ventricular dilation, and decline in left ventricular ejection fraction.
- Transthyretin cardiac amyloidosis
- Dilated cardiomyopathy
- Heart failure with reduced ejection fraction
These studies also address cardiac amyloid cardiomyopathy and disease expression in asymptomatic genetic carriers.
Lung transplant rejection and bronchiolitis obliterans syndrome
Clinical research includes patients after lung transplantation with established bronchiolitis obliterans syndrome, reflecting interest in chronic rejection and airway-related graft dysfunction.
- Lung transplant chronic rejection
- Bronchiolitis obliterans syndrome
- Mesenchymal stromal cells
Work in this area examines endobronchial administration of allogeneic mesenchymal stromal cells for transplant-related airway disease.
Bone regeneration and fracture healing
The sponsor is involved in studies of delayed union and non-union long bone fractures, with a focus on restoring radiological consolidation after surgical treatment.
- Long bone fracture non-union
- Delayed fracture consolidation
- Bone marrow mesenchymal cells
Research in this field includes biomaterial-assisted bone healing and allogeneic mesenchymal cell applications in orthopaedic repair.
