HIV Treatment and Care Delivery
Research focuses on human immunodeficiency virus management in people living with HIV, including long-acting antiretroviral strategies, treatment acceptability, and outpatient administration models. The portfolio also includes studies on inflammatory pathways and reservoir-related outcomes in suppressed patients.
- Long-acting cabotegravir and rilpivirine
- Baricitinib in people with HIV
- HIV reservoir and immune activation
Additional work addresses patient experience, safety, and treatment practicality in routine HIV care.
Post-viral Conditions and COVID-19
The sponsor supports research in post-COVID-19 condition and broader recovery after SARS-CoV-2 infection, with attention to persistent functional limitation, symptom burden, and health status outcomes. Trials also include antiviral use in transplant recipients with recent infection.
- Post-COVID-19 condition
- Functional recovery after COVID-19
- Remdesivir in kidney transplant recipients
These studies reflect interest in both chronic sequelae and clinical management of infection in medically vulnerable populations.
Sexually Transmitted Infections
Clinical activity includes treatment research in syphilis, with emphasis on alternative antibacterial options for early disease and cure outcomes. This area aligns with infectious disease care in populations affected by overlapping sexually transmitted and chronic viral infections.
- Early syphilis
- Alternative oral antibiotics
- Infectious disease treatment options
The sponsor’s interest extends to practical therapeutic choices that support accessible management of bacterial infection.
Neurocognitive Disorders
Research also addresses mild cognitive impairment linked to Alzheimer disease, with attention to cognitive symptoms, plasma biomarkers, and immune-related signals. This therapeutic area connects neurodegeneration with infectious disease–associated cognitive decline.
- Mild cognitive impairment
- Alzheimer-related biomarkers
- Cognitive and neuroinflammatory outcomes
These studies explore biologic changes relevant to memory, thinking, and neurocognitive function.
Metabolic and Liver Health in People Living with HIV
The sponsor funds research on liver steatosis, liver fibrosis, and metabolic outcomes in asymptomatic individuals with HIV who are switching antiretroviral regimens. This work includes evaluation of hepatic and cardiometabolic status alongside general HIV-related health measures.
- Liver steatosis
- Liver fibrosis
- Metabolic outcomes in HIV
Interest in this area reflects the clinical overlap between chronic HIV care and long-term hepatic and metabolic complications.
