Knee osteoarthritis and regenerative joint therapy
Clinical research in osteoarthritis focuses on mesenchymal stem cell therapy, comparing allogeneic and autologous cell-based approaches with hyaluronic acid in patients with knee osteoarthritis.
- Mesenchymal stem cells
- Cartilage and joint repair
- Functional and radiological outcomes
The sponsor’s activity in this area is centered on musculoskeletal disease and biologic strategies for joint preservation.
Relapsed or refractory B-cell lymphoma and cellular immunotherapy
Research in hematologic malignancy includes CAR-T cell development for relapsed or refractory B-cell lymphoma, with interest in CD19-directed immune targeting and genetically modified T lymphocytes.
- Chimeric antigen receptor therapy
- Genetically modified T cells
- CD19-positive B-cell disease
These studies place emphasis on advanced cell therapy for aggressive lymphoid cancers.
Dry eye disease in graft-versus-host disease
Ocular research addresses severe dry eye disease associated with chronic graft-versus-host disease, using subconjunctival adipose-derived stromal cells to evaluate relief of ocular surface symptoms and signs.
- Ocular involvement in cGVHD
- Subconjunctival cell therapy
- Inflammatory eye disease
The therapeutic focus is on ophthalmology and immune-mediated eye complications.
Symptomatic cholelithiasis and laparoscopic cholecystectomy
Perioperative research in biliary surgery examines near-infrared fluorescence cholangiography during laparoscopic cholecystectomy for symptomatic cholelithiasis, with attention to visualization of the extrahepatic biliary tree.
- Fluorescence-guided surgery
- Biliary anatomy visualization
- Minimally invasive gallbladder surgery
This area reflects interest in surgical imaging and operative support for hepatobiliary disease.
