Oncology and tumour immunotherapy
Solid tumours are a major focus, including advanced solid tumours, germ cell tumours, metastatic uveal melanoma, and cutaneous squamous cell carcinoma. The portfolio also includes studies in tumour immune resistance and anti-PD-1 therapy.
- Advanced solid tumours
- Germ cell tumours
- Metastatic uveal melanoma
- Cutaneous squamous cell carcinoma
Research activity in this area includes cell-based immunotherapy, tumour response assessment, and the study of biomarkers linked to treatment resistance.
Renal medicine and transplantation
Several trials address kidney transplantation and related complications, including post-transplant diabetes, graft pyelonephritis, metabolic syndrome in transplant candidates, and latent tuberculosis infection in people with end-stage kidney disease.
- Kidney transplantation
- Post-transplant diabetes
- Graft pyelonephritis
- Latent tuberculosis infection
The sponsor also studies metabolic risk in transplant populations and infection-related outcomes in renal care.
Neuromuscular and rare neurological disease
Investigator interest extends to rare and chronic neurological disorders such as adrenomyeloneuropathy, generalized myasthenia gravis, and Type C Niemann-Pick disease, with attention to both functional symptoms and cognitive impairment.
- Adrenomyeloneuropathy
- Generalized myasthenia gravis
- Type C Niemann-Pick disease
These studies reflect interest in neuromuscular weakness, neurodegeneration, and disease-related disability.
Respiratory and lymphatic disorders
The sponsor funds research in lymphangioleiomyomatosis, a rare progressive lung disease, including work related to symptom control and treatment safety in combination with established therapies.
- Lymphangioleiomyomatosis
This area links pulmonary disease with rare-disease management and long-term therapeutic monitoring.
Infectious disease prevention and mental health
Additional studies cover HPV infectivity and transmission, HPV vaccination, and treatment of major depressive disorder with moderate to severe insomnia.
- Human papillomavirus infection and vaccination
- Major depressive disorder with insomnia
These topics include infection prevention, sleep disturbance, and psychiatric symptom management.
