Fondazione Ricerca e Innovazione Cardiovascolare

Coronary artery disease and post-PCI care

Research activity is centered on patients with stable or unstable coronary syndromes after successful percutaneous coronary intervention, with attention to long-term treatment choices in this setting.

  • Coronary syndromes
  • Post-PCI antithrombotic management
  • Ischaemic risk reduction

The sponsor’s funded research reflects a clinical interest in optimizing secondary prevention for patients recovering from coronary revascularisation.

Antiplatelet therapy strategies

The trial portfolio focuses on comparing single antiplatelet therapy and dual antiplatelet therapy in the context of coronary disease, with emphasis on balancing protection from thrombotic events and treatment-related harm.

  • Single antiplatelet therapy
  • Dual antiplatelet therapy
  • Thrombotic event prevention

Interest extends to treatment selection in older patients and in those with heightened vulnerability to adverse effects from intensified antithrombotic treatment.

Bleeding risk and clinical safety

A major therapeutic focus is the reduction of bleeding complications while maintaining cardiovascular protection, particularly in patients at increased risk of haemorrhagic events.

  • Clinically relevant bleeding
  • High bleeding risk patients
  • Net clinical benefit

The funded research examines safety outcomes alongside cardiovascular efficacy, reflecting an interest in treatment regimens that are better suited to fragile patient groups.

Cardiovascular outcomes and event prevention

Clinical outcomes of interest include major adverse cardiovascular events and composite measures that capture both ischaemic and bleeding endpoints, supporting a broad assessment of patient benefit after coronary intervention.

  • Major adverse cardiovascular events
  • Composite clinical outcomes
  • Secondary prevention

This area of research aligns with efforts to refine antithrombotic care for older adults and other patients in whom treatment intensity must be carefully matched to risk.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study Comparing Single and Dual Antiplatelet Therapy with Clopidogrel and Acetylsalicylic Acid in Elderly Patients or Those at Risk of Bleeding After Balloon Surgery

    Recruiting

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    Belgium Italy Luxembourg Spain