Fondazione IRCCS Istituto Nazionale Dei Tumori

Oncologic Surgery and Perioperative Care

Research activity includes oncologic surgery with interest in reducing postoperative morbidity, managing inflammatory risk, and improving recovery after major cancer operations.

  • Postoperative morbidity
  • Inflammatory state
  • Perioperative risk reduction
  • Major oncologic surgery

Clinical work in this area also addresses patients undergoing complex surgical treatment for advanced abdominal and pelvic malignancies.

Genitourinary and Renal Cancers

The sponsor is active in bladder cancer, renal cell carcinoma, collecting duct carcinoma, renal medullary carcinoma, and metastatic thyroid cancer, with additional interest in refractory and pretreated disease.

  • Muscle-invasive bladder cancer
  • Renal cell carcinoma
  • Collecting duct carcinoma
  • Metastatic thyroid cancer

Its research also extends to advanced urothelial and non-urothelial histologies and to disease settings involving prior exposure to immune-based treatment.

Breast, Gynecologic, and Gastrointestinal Cancers

Key interests include triple negative breast cancer, endometrial cancer, ovarian cancer, cervical carcinoma, colorectal cancer, and rectal cancer, reflecting broad engagement across solid tumors in women’s and digestive oncology.

  • Triple negative breast cancer
  • Ovarian cancer
  • Locally advanced cervical carcinoma
  • Colorectal and rectal cancer

Research also covers high-risk disease after surgery and molecularly selected colorectal settings with persistent residual disease.

Thoracic, Neuroendocrine, and Rare Tumors

The portfolio includes non-small cell lung cancer, Merkel cell carcinoma, gastroenteropancreatic neuroendocrine tumors, thoracic neuroendocrine tumors, medulloblastoma, and diffuse intrinsic pontine glioma.

  • Non-small cell lung cancer
  • Merkel cell carcinoma
  • Neuroendocrine tumors
  • Pediatric brain tumors

This area also includes rare and aggressive cancers requiring specialized multidisciplinary management.

Lymphoma, Sarcoma, and Peritoneal Disease

Additional activity focuses on Hodgkin and non-Hodgkin lymphoma, mantle-cell lymphoma, peripheral T-cell lymphoma, soft tissue sarcoma, and pseudomyxoma peritonei.

  • Relapsed or refractory lymphoma
  • High-risk soft tissue sarcoma
  • Pseudomyxoma peritonei
  • Peritoneal metastases

Research in this group also includes conditions linked to advanced peritoneal spread and challenging relapsed hematologic malignancies.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study of Pembrolizumab and Enfortumab Vedotin for Patients with Collecting Duct and Renal Medullary Carcinoma

    Not yet recruiting

    2 1 1 1
    Investigated Drugs:
    Italy
  • Study of Cabozantinib for Patients with Advanced Renal Cell Carcinoma Previously Treated with One Immunotherapy Drug

    Not recruiting

    2 1 1 1
    Investigated Diseases:
    Investigated Drugs:
    Italy
  • Study of Selinexor, Ifosfamide, Etoposide, and Dexamethasone for Patients with Relapsed or Refractory Peripheral T-cell Lymphomas

    Not recruiting

    2 1 1 1
    Italy
  • Study on Radiotherapy with Nimotuzumab and Vinorelbine for Newly Diagnosed Childhood and Adolescent Diffuse Intrinsic Pontine Glioma (DIPG) Patients

    Not recruiting

    2 1 1 1
    Investigated Diseases:
    Italy
  • Study on Triple Negative Breast Cancer Treatment with Chemotherapy, Fasting-Mimicking Diet, and Metformin for Preoperative Patients

    Not recruiting

    2 1 1 1
    Investigated Diseases:
    Investigated Drugs:
    Italy
  • Study on KTE-X19 CAR-T Cell Therapy for Patients with Relapsed or Refractory Mantle Cell Lymphoma Responding Partially to Ibrutinib

    Not recruiting

    2 1 1 1
    Italy