Kidney Transplantation and Viral Infection Prevention
Research activity in kidney transplantation focuses on BK polyomavirus infection prevention and the role of adaptive immunity under routine immunosuppressive regimens, including mTOR inhibitors.
- BK virus immunity
- Polyomavirus prevention
- Post-transplant viral infection
The sponsor’s interest in this area is centered on immune control of viral reactivation in the transplant setting.
Paediatric Oncology
Clinical research includes relapsed/refractory neuroblastoma and other solid tumours in children, with attention to treatment strategies for difficult-to-manage paediatric cancers.
- Neuroblastoma
- Solid tumours
- Relapsed/refractory disease
This area reflects a therapeutic focus on high-risk childhood malignancies requiring new treatment options.
Targeted Therapy and Combination Oncology
Work in oncology also covers targeted therapies and combination approaches with chemotherapy, including irinotecan and temozolomide, in the context of paediatric solid tumours.
- Targeted anticancer therapies
- Chemotherapy combinations
- Tumour-directed treatment
The sponsor’s oncology portfolio includes interest in treatment settings where multimodal therapy is relevant.
Immunomodulation in Transplant Medicine
Another area of interest is the interaction between immune responses and immunosuppressive therapy after kidney transplantation, with emphasis on how treatment regimens affect protection against BK polyomavirus.
- Adaptive immune response
- Transplant immunology
- Immunosuppressive regimens
This research domain links infectious risk with transplant immunology and post-transplant care.
