Fakultni Nemocnice V Motole

Paediatric cystic fibrosis and musculoskeletal health

Clinical research in cystic fibrosis with attention to bone metabolism, bone density, and skeletal muscle force in children.

  • Bone health
  • Mineral metabolism
  • Muscle strength

Interest also extends to nutritional and metabolic factors linked to skeletal complications in long-term paediatric care.

Spinal cord injury and spastic motor behaviour

Trials in sub-acute cervical and thoracic spinal cord injury focus on spastic motor behaviour, particularly the dynamic component affecting movement control.

  • Spasticity management
  • Neurological rehabilitation
  • Motor function disorders

The clinical interest is centred on pharmacological control of post-injury motor symptoms in patients with incomplete spinal lesions.

Friedreich’s ataxia and mitochondrial biology

Research activity includes Friedreich’s ataxia with emphasis on mitochondrial function and biological markers linked to treatment response.

  • Neurodegenerative disease
  • Mitochondrial biomarkers
  • Cellular energy metabolism

This area reflects a focus on identifying measurable signals of disease-related metabolic change in inherited neurological disorders.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study to evaluate the effect of omaveloxolone on mitochondrial function in patients with Friedreich’s ataxia

    Recruiting

    3 1 1 1
    Investigated drugs:
    Czechia Poland
  • Comparison of Pregabalin and Baclofen Treatment in Patients with Spastic Motor Behavior Following Cervical or Thoracic Spinal Cord Injury

    Recruiting

    3 1 1 1
    Investigated diseases:
    Investigated drugs:
    Czechia
  • Study on Improving Bone Health in Children with Cystic Fibrosis Using Cholecalciferol

    Recruiting

    3 1 1 1
    Investigated diseases:
    Investigated drugs:
    Czechia