Acromegaly and growth hormone-related disorders
Clinical research includes treatment of acromegaly, with attention to control of IGF-1 activity, symptom burden, and longer-term safety and tolerability in adults living with persistent hormone excess.
- Acromegaly symptom control
- IGF-1 normalization
- Long-term safety and tolerability
Work in this area centers on endocrine regulation and disease control in pituitary-driven hormone imbalance.
Congenital adrenal hyperplasia and adrenal hormone excess
The sponsor studies classic congenital adrenal hyperplasia and broader congenital adrenal hyperplasia populations, including pediatric and adult participants, with focus on adrenal androgen control and reduction of glucocorticoid burden while maintaining hormonal balance.
- Classic congenital adrenal hyperplasia
- Adrenal androgen regulation
- Glucocorticoid management
Research interest extends to endocrine disorders involving adrenal steroid dysregulation and chronic hormone replacement needs.
Carcinoid syndrome and neuroendocrine symptom management
Trials address carcinoid syndrome with emphasis on reducing flushing episodes and managing symptoms associated with neuroendocrine disease.
- Carcinoid syndrome
- Flushing reduction
- Neuroendocrine symptom control
This area reflects interest in hormonal and vasoactive manifestations of neuroendocrine tumors.
SST2-positive neuroendocrine neoplasms and solid tumors
Research includes adults with SST2-positive neuroendocrine neoplasms and other SST2-expressing relapsed or refractory solid tumors, covering advanced disease settings and tumor biology linked to somatostatin receptor expression.
- SST2-positive neuroendocrine neoplasms
- SST2-expressing solid tumors
- Advanced neuroendocrine oncology
These studies focus on oncologic conditions defined by receptor-targeted therapeutic interest.
