Centre Hospitalier Universitaire Grenoble Alpes

Neurology and Neurocritical Care

Clinical research spans stroke, subarachnoid hemorrhage, head trauma, herpes simplex virus encephalitis, and neurocognitive disorders with agitation in older adults. Additional interest includes acute anterior ischemic optic neuropathy and hyponatremia in the setting of cerebral hemorrhage.

  • Stroke and subarachnoid hemorrhage
  • Traumatic brain injury and head trauma
  • Encephalitis and acute neurocognitive disorders
  • Optic neuropathy

Research activity also covers symptom control and supportive care in acute neurological illness, including management of pain, agitation, and metabolic complications.

Respiratory and Critical Care

The sponsor supports studies in chronic obstructive pulmonary disease and respiratory distress syndrome in very preterm infants. Work in intensive care also includes sedation, ventilation support, and early respiratory stabilization.

  • Chronic obstructive pulmonary disease
  • Preterm neonatal respiratory distress
  • Non-invasive ventilation support
  • Airway and sedation management

These studies reflect interest in respiratory outcomes across adult and neonatal critical care settings.

Cardiovascular and Thromboembolic Disease

Research includes atherosclerotic cardiovascular disease, atrial fibrillation, coronary microvascular dysfunction, and prevention of venous thromboembolism after severe trauma. The portfolio also addresses vascular complications linked to acute neurological disease.

  • Atherosclerotic cardiovascular disease
  • Atrial fibrillation
  • Coronary microvascular dysfunction
  • Venous thromboembolism prevention

Clinical interests extend to cardiovascular risk management in patients requiring invasive diagnostic evaluation or recovering from major injury.

Oncology and Transplantation

Oncology-focused studies include breast cancer, pancreatic ductal adenocarcinoma, and unresectable hepatocellular carcinoma. The sponsor also supports research in highly sensitized patients on the kidney transplant waiting list.

  • Breast cancer
  • Pancreatic ductal adenocarcinoma
  • Hepatocellular carcinoma
  • Kidney transplantation and HLA sensitization

These areas show interest in advanced solid tumors and complex immunological challenges in transplantation.

Rheumatology, Psychiatry, and Geriatric Care

Additional research covers symptomatic digital osteoarthritis, depression, and care delivery in older adults with moderate-to-severe neurocognitive disorders. The portfolio also includes treatment-related questions in these chronic and age-related conditions.

  • Digital osteoarthritis
  • Depressive disorders
  • Neurocognitive disorders in older adults

These studies focus on musculoskeletal symptoms, mental health, and practical care needs in ageing populations.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Urea for Treating Low Sodium Levels in Patients with Brain Hemorrhage

    Not recruiting

    2 1
    Investigated Diseases:
    Investigated Drugs:
    France
  • Study on Dexamethasone for Patients with Herpes Simplex Virus Encephalitis

    Not recruiting

    3 1 1 1
    Investigated Diseases:
    Investigated Drugs:
    France
  • Study on the Effects of Bosentan for Patients with Early Stage Non-Arteritic Anterior Ischemic Optic Neuropathy

    Not recruiting

    3 1 1 1
    Investigated Diseases:
    Investigated Drugs:
    France
  • Study on the Effect of Evolocumab on Heart Disease in Patients Needing Coronary Angiography

    Not recruiting

    2 1 1 1
    Investigated Diseases:
    Investigated Drugs:
    France
  • Study on the Effectiveness and Safety of Oral Midazolam for Elderly Patients with Severe Neurocognitive Disorders and Care Resistance

    Not recruiting

    2 1 1 1
    Investigated Diseases:
    Investigated Drugs:
    France
  • Study of Ezurpimtrostat with Atezolizumab and Bevacizumab for Patients with Unresectable Liver Cancer

    Not recruiting

    2 1 1 1
    Investigated Diseases:
    France