Centre Hospitalier Universitaire De Nantes

Hematologic Malignancies and Cellular Therapy

Acute myeloid leukemia, acute leukemia, multiple myeloma, and mantle cell lymphoma are central areas of interest, alongside transplant-linked care for high-risk blood cancers. The portfolio also includes studies in minimal residual disease assessment and allogeneic stem cell transplantation.

  • Acute myeloid leukemia
  • Multiple myeloma
  • Mantle cell lymphoma
  • Allogeneic stem cell transplantation
  • Minimal residual disease

Research activity extends to immune-based and transplant-adjacent approaches in patients with relapsed, refractory, or high-risk hematological disease.

Transplantation and Immunosuppression

The sponsor is active in kidney transplant, heart transplant, pancreatic transplant, and management of graft dysfunction and chronic renal failure. Work also covers immunosuppressive strategies and prevention of transplant-related complications.

  • Kidney transplant
  • Heart transplant
  • Pancreatic transplant
  • Graft dysfunction
  • Immunosuppression

Clinical research includes renal and cardiac graft preservation, rejection-related care, and post-transplant immune modulation.

Infectious Disease and Perioperative Care

Studies address hospital-acquired pneumonia, community-acquired pneumonia, MRSA, and staphylococcal endocarditis, with additional interest in perioperative infection control and antimicrobial selection. Surgical settings include cardiac, orthopedic, and transplant-related care.

  • Hospital-acquired pneumonia
  • Community-acquired pneumonia
  • MRSA
  • Staphylococcal endocarditis
  • Perioperative infection prevention

The research landscape also includes microbial decolonization, antifungal prophylaxis, and infection management in hospitalized adults.

Respiratory, Critical Care, and Emergency Medicine

Another major focus is severe asthma, traumatic brain injury, severe burns, and acute metabolic or respiratory instability requiring hospital-based intervention. The sponsor also supports work in hyperkalemia and urgent airway management.

  • Severe asthma
  • Traumatic brain injury
  • Severe burns
  • Hyperkalemia
  • Rapid sequence induction

These studies reflect interest in acute care pathways, critical illness, and treatment strategies for unstable patients in emergency and intensive care settings.

Autoimmune, Gastrointestinal, Pain, and Surgical Conditions

Research includes multiple sclerosis, atopic dermatitis, ulcerative colitis with recurrent pouchitis, severe primary dysmenorrhea, and postoperative pain syndromes. Surgical topics also include cardiac surgery, orthopedic trauma surgery, and shoulder arthroplasty.

  • Multiple sclerosis
  • Atopic dermatitis
  • Ulcerative colitis
  • Severe primary dysmenorrhea
  • Postoperative pain

Additional activity covers functional and behavioral conditions such as gambling disorder, as well as surgical infection prevention and pain control in complex procedures.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Testing Psilocybin with Therapy for Treatment of Gambling Disorder in Adults with Problem Gambling

    Not yet recruiting

    2 1
    France
  • Testing the effectiveness and safety of remimazolam, ketamine, and propofol for rapid sequence induction in patients at risk of aspiration

    Not yet recruiting

    2 1 1 1
    France
  • Study of romiplostim given before heart surgery in patients with low platelet counts to improve blood clotting after surgery

    Not yet recruiting

    2 1 1
    Investigated diseases:
    France
  • Study of ixazomib, iberdomide and dexamethasone combination in elderly patients with first relapse of multiple myeloma

    Not yet recruiting

    2 1 1
    France
  • Study of Baricitinib for Treating Hospital-Acquired Pneumonia in Critically Ill Patients with a Proinflammatory Profile

    Not yet recruiting

    4 1 1 1
    Investigated drugs:
    Belgium France The Netherlands Spain
  • Study on Insulin Aspart, Salbutamol, and Glucose for Treating Acute Hyperkalemia in Emergency Department Patients

    Not recruiting

    3 1 1 1
    France