Centre Hospitalier Universitaire De Lille

Hematologic malignancies

Clinical research includes multiple myeloma and acute myeloid leukemia, with interest in CD19-directed cellular therapy, bispecific antibodies, and combinations used in patients with relapsed or newly diagnosed disease.

  • Multiple myeloma
  • Acute myeloid leukemia
  • CAR-T cell therapy
  • CD19-targeted treatment

Work in this area also reflects attention to frail and older patients needing less intensive treatment options.

Neurology and cerebrovascular disease

The sponsor studies Alzheimer’s disease, Parkinson’s disease, stroke, and intracerebral haemorrhage, alongside research on cognitive decline, motor fluctuation, and post-hemorrhagic brain injury.

  • Alzheimer’s disease
  • Parkinson’s disease
  • Stroke
  • Intracerebral haemorrhage

Its neurological portfolio also includes approaches related to dopaminergic stimulation and recovery after brain bleeding.

Respiratory and thoracic oncology

Research activity covers chronic obstructive pulmonary disease, advanced non-small-cell lung cancer, and malignant pleural mesothelioma, with interest in both symptom control and treatment-resistant thoracic cancer.

  • COPD
  • Non-small-cell lung cancer
  • Malignant pleural mesothelioma
  • Immunotherapy

These studies indicate involvement in pulmonary function assessment and combined local and systemic cancer treatment strategies.

Dermatology and rare mucocutaneous disease

Trials address actinic keratosis and vulvar extramammary Paget’s disease, with additional work in cervico-facial lymphatic malformations that require specialized local therapy.

  • Actinic keratosis
  • Extramammary Paget’s disease
  • Lymphatic malformations
  • Photodynamic therapy

The dermatologic and rare disease portfolio includes lesions affecting the scalp, forehead, vulva, and cervico-facial region.

Inflammatory, hepatic, and urologic disorders

Additional research focuses on alcoholic hepatitis, polycystic ovary syndrome, and neuro-urology in patients with multiple sclerosis or spinal cord injury.

  • Alcoholic hepatitis
  • Polycystic ovary syndrome
  • Detrusor overactivity
  • Multiple sclerosis

This area also includes management of urinary complications associated with impaired bladder control and chronic neurological disease.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study of N-acetylcysteine and prednisolone combination versus extended prednisolone treatment in patients with severe alcoholic hepatitis

    Recruiting

    3 1 1
    France
  • Study on Avoiding Anticoagulation with Apixaban for Patients with Intracerebral Hemorrhage

    Recruiting

    3 1 1 1
    Investigated diseases:
    Investigated drugs:
    France
  • A study to evaluate the use of diroximel fumarate to reduce brain swelling in patients with a stroke caused by bleeding in the brain.

    Recruiting

    3 1 1
    Investigated drugs:
    France
  • Study on the Effects of Inhaled Budesonide, Glycopyrronium Bromide, and Formoterol Fumarate Dihydrate in Patients with Stable COPD

    Recruiting

    3 1 1 1
    France
  • Study of Teclistamab with Daratumumab or Lenalidomide for Elderly Patients with Newly Diagnosed Multiple Myeloma

    Recruiting

    2 1 1 1
    France
  • Study of Intrapleural Photodynamic Therapy with Aminolevulinic Acid Hydrochloride and Nivolumab for Patients with Malignant Pleural Mesothelioma

    Recruiting

    2 1 1 1
    Investigated diseases:
    France