Centre Hospitalier Regional Universitaire

Oncology and immunotherapy

The sponsor funds studies in hepatocellular carcinoma, biliary tract carcinoma, glioblastoma, colorectal cancer, and melanoma, with strong interest in immune checkpoint inhibition, therapeutic cancer vaccines, and combinations with anti-angiogenic therapy or chemotherapy.

  • Hepatocellular carcinoma
  • Glioblastoma
  • Colorectal cancer
  • Cutaneous melanoma
  • Biliary tract carcinoma

Research activity also includes metastatic disease, unresectable tumors, and neoadjuvant or maintenance immunotherapy strategies.

Digestive system and gastrointestinal cancer surgery

Clinical work in colorectal surgery and esophageal cancer focuses on surgical outcomes, perioperative support, and treatment intensification for advanced gastrointestinal malignancies, including anal canal cancer and esophageal carcinoma.

  • Colorectal surgery
  • Esophageal cancer
  • Anal canal cancer
  • Metastatic colorectal carcinoma

Topics include anastomotic integrity, chemoradiotherapy, and multimodal treatment for locally advanced digestive tumors.

Urologic oncology and renal transplantation

The sponsor supports research in penile squamous cell carcinoma and kidney transplantation, combining interest in cancer treatment with post-transplant care and immune-related complications.

  • Penile squamous cell carcinoma
  • Renal transplant
  • Post-transplant diabetes
  • Immunosuppression

Research also addresses lymphocyte depletion prevention and metabolic follow-up after transplantation.

Cardiology and heart failure

One area of interest is chronic decompensated heart failure in older adults, with attention to early treatment pathways in the emergency setting and cardiometabolic management.

  • Chronic decompensated heart failure
  • Emergency department care
  • Gliflozin therapy
  • Elderly patients

Work in this field connects cardiovascular disease with practical inpatient and outpatient care transitions.

Renal disease and metabolic complications

The sponsor is involved in studies of renal insufficiency and transplantation-related metabolic risk, including prevention of new-onset diabetes after kidney transplantation.

  • Renal insufficiency
  • Kidney transplantation
  • Post-transplant diabetes
  • Metabolic monitoring

These studies reflect interest in renal function, transplant follow-up, and endocrine complications in immunologically vulnerable patients.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on Regorafenib with Capecitabine, Cyclophosphamide, and Aspirin for Patients with Metastatic Colorectal Cancer Resistant to Chemotherapy

    Recruiting

    3 1 1 1
    France
  • Study of Chemoradiation with Carboplatin and Paclitaxel for Elderly Patients with Esophageal Cancer

    Recruiting

    1 1 1 1
    Investigated Diseases:
    Investigated Drugs:
    France
  • Study on UCPVax, Atezolizumab, and Bevacizumab for Patients with Unresectable Liver Cancer

    Recruiting

    2 1 1 1
    France
  • A feasibility study of dapagliflozin for elderly patients hospitalized with chronic heart failure.

    Not yet recruiting

    3 1 1 1
    Investigated Diseases:
    France
  • Testing UCPVax vaccine with or without pembrolizumab and temozolomide in patients with unmethylated MGMT glioblastoma after initial treatment

    Not yet recruiting

    2 1 1 1
    Investigated Diseases:
    France
  • Study of Pembrolizumab for Patients with High-Risk Stage IIB/IIC Melanoma

    Not yet recruiting

    2 1 1 1
    Investigated Diseases:
    Investigated Drugs:
    France