Centre for Human Drug Research

Neuropathic pain and analgesic research

Clinical studies in chronic neuropathic pain, chronic pain, and neuropathic pain focus on pain relief, sensory profiling, and differences in treatment response across patient subgroups.

  • Chronic neuropathic pain
  • Quantitative sensory testing
  • Pain phenotyping
  • Analgesic effects

Research also includes evaluation of established pain medicines and experimental approaches to pain measurement in healthy volunteers and patients.

Cannabinoid and central nervous system studies

Trials examine cannabidiol and THC in relation to central nervous system function, including cognitive performance, neural excitability, and pain-related outcomes.

  • Cannabidiol
  • THC
  • CNS task performance
  • Transcranial magnetic stimulation

The research portfolio also covers interactions with other medicines used in pain and neurological settings.

Depression and neuropsychiatric assessment

Work in major depressive disorder includes studies of treatment-related effects on mood-related outcomes and neurobehavioral measures.

  • Major depressive disorder
  • Neuropsychiatric assessment
  • Ketamine
  • Antidepressant response

These studies connect psychiatric symptoms with measurable changes in brain function and clinical performance.

Cardiovascular, metabolic, and vascular research

Investigations in cardiovascular and metabolic diseases address vascular responses, microcirculation, and metabolic modulation in controlled clinical settings.

  • Cardiovascular and metabolic diseases
  • Vascular reactivity
  • Microvascular responses
  • Metabolic signaling

Related studies include assessments of inflammatory stimuli and their effects on blood vessel function.

Immunology and neuroimmune assessment

Research spans immuno-oncology assessments, immunological/cardiovascular conditions, and neuroimmune responses, with attention to inflammatory and physiological readouts.

  • Immuno-oncology assessments
  • Immunological responses
  • Inflammation
  • Neuroimmune interaction

These studies include evaluation of immune activation alongside pain, vascular, and neurological measures.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on the Effects of THC 2% Oil for Patients with Chronic Neuropathic Pain

    Recruiting

    Investigated drugs:
    The Netherlands
  • Study on the Effects of Cannabidiol on the Central Nervous System in Healthy Male Participants

    Not recruiting

    Investigated diseases:
    Investigated drugs:
    The Netherlands