Bolt Biotherapeutics Inc.

HER2-Positive Breast Cancer

Clinical research in human epidermal growth factor receptor 2-positive metastatic breast cancer, with interest in patients who have received prior HER2-directed treatment.

  • HER2-positive metastatic breast cancer
  • Previously treated disease
  • Anti-tumor activity

The sponsor’s studies in this area focus on treatment options for advanced breast malignancies driven by HER2 expression.

Advanced HER2-Expressing Solid Tumors

Research extends beyond breast cancer to a broader set of HER2-expressing solid tumors, reflecting interest in tumor types defined by this molecular target.

  • Advanced solid tumors
  • HER2 expression
  • Solid tumor oncology

These studies address advanced cancers with HER2-driven biology across multiple tumor settings.

Combination Immuno-Oncology

The sponsor investigates combinations that pair HER2-targeted therapy with immune checkpoint inhibition, including research involving nivolumab.

  • Immune checkpoint inhibition
  • Combination therapy
  • Nivolumab-based regimens

This area reflects an interest in integrating targeted and immune-based approaches for solid tumor oncology.

Targeted Antibody Therapeutics

Research activity centers on antibody-based oncology therapeutics designed to engage HER2-positive malignancies.

  • Monotherapy development
  • Targeted biologics
  • HER2-directed treatment strategies

These trials support investigation of biotherapeutic approaches in advanced cancer care.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study of BDC-1001 and Nivolumab for Patients with Advanced HER2-Positive Solid Tumors

    Not recruiting

    1 1 1 1
    Investigated diseases:
    Investigated drugs:
    France
  • Study of BDC-1001 and Pertuzumab for Patients with HER2-Positive Metastatic Breast Cancer Previously Treated with Trastuzumab Deruxtecan

    Not recruiting

    2 1 1 1
    Investigated drugs:
    France Italy Spain