Azienda Ospedaliero-Universitaria Maggiore Della Carita

Cardiovascular medicine

Clinical research at Azienda Ospedaliero-Universitaria Maggiore Della Carita includes acute myocardial infarction, ST-elevation myocardial infarction, non-ST-elevation myocardial infarction, and unstable angina. The sponsor also studies primary percutaneous coronary intervention and coronary plaque inflammation, with attention to platelet reactivity, heart failure, and myocardial injury.

  • Acute coronary syndromes
  • Myocardial infarction
  • Coronary intervention
  • Antiplatelet therapy

Research activity in this area reflects a focus on cardiometabolic risk and treatment strategies relevant to hospitalized patients with acute ischemic heart disease.

Metabolic and inflammatory disease

The sponsor funds studies in diabetes mellitus and the use of SGLT-2 inhibitors, alongside investigations into inflammatory pathways linked to cardiovascular disease. Its portfolio also includes work on oral semaglutide and anti-inflammatory effects within coronary disease settings.

  • Diabetes mellitus
  • SGLT-2 inhibition
  • GLP-1 receptor agonism
  • Inflammation in atherosclerosis

These studies connect metabolic control with vascular protection and the modulation of inflammatory burden in patients with cardiovascular comorbidity.

Neurodegenerative disorders

Research also covers Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, with interest in symptom management and quality of life in people living with progressive neurodegenerative diseases. The sponsor’s work includes evaluation of cannabis-based therapy in this patient population.

  • Alzheimer’s disease
  • Parkinson’s disease
  • Amyotrophic lateral sclerosis
  • Cannabinoid-based treatment

This area emphasizes neurological symptom burden, functional well-being, and treatment tolerability in chronic central nervous system disorders.

Infectious disease and critical illness

Another major area of interest is acute care for pneumonia and sepsis, including infections in elderly patients and cases associated with presumed infectious causes. The sponsor studies approaches aimed at inflammation, hospital recovery, and mortality risk in seriously ill patients.

  • Pneumonia
  • Sepsis
  • Inflammatory markers
  • Hospitalized older adults

Work in this domain reflects interest in supportive treatment for acute infectious syndromes and the clinical course of fragile inpatients.

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Matched clinical trials

  • A Study of Semaglutide for Diabetic Patients with Heart Attack or Unstable Angina to Measure Changes in Coronary Artery Plaque Using Imaging

    Not yet recruiting

    1 1 1 1
    Investigated drugs:
    Italy
  • Study of early dapagliflozin treatment to reduce heart damage in patients with acute heart attack and reduced heart pumping function

    Not yet recruiting

    1 1 1 1
    Investigated diseases:
    Investigated drugs:
    Italy
  • Study of vitamin D3 (cholecalciferol) as additional treatment for elderly patients with pneumonia or sepsis due to infection

    Not yet recruiting

    1 1 1
    Investigated diseases:
    Investigated drugs:
    Italy
  • Study on Cannabis Extract for Improving Quality of Life in Patients with Alzheimer’s, Parkinson’s, or ALS Using Dronabinol and Cannabidiol

    Not yet recruiting

    Investigated drugs:
    Italy
  • Study on Early vs. Delayed Ticagrelor with Cangrelor for Patients with STEMI Undergoing PCI

    Not yet recruiting

    1 1 1 1
    Investigated diseases:
    Italy