Algemeen ziekenhuis Rivierenland

Regional Anesthesia and Nerve Block Optimization

The institution demonstrates specialized expertise in advancing regional anesthesia techniques, with particular emphasis on optimizing interscalene plexus blocks for surgical procedures. Research efforts concentrate on refining perineural administration protocols to enhance the duration and quality of postoperative analgesia. This work addresses the critical clinical need for effective pain management strategies that minimize systemic opioid requirements while maximizing patient comfort following surgical interventions.

  • Interscalene Brachial Plexus Blocks
  • Perineural Adjuvant Therapy
  • Analgesic Block Duration Enhancement

The research specifically investigates dose-response relationships for adjuvant medications administered alongside local anesthetics, seeking to establish optimal therapeutic windows that balance efficacy with safety. This pharmacological optimization work contributes to the broader field of perioperative pain management and patient recovery protocols.

Orthopedic Surgical Pain Management

Clinical investigation focuses on patients undergoing shoulder surgery, a population requiring robust postoperative pain control due to the inherently painful nature of upper extremity orthopedic procedures. The research addresses the specific challenges associated with maintaining adequate analgesia during the critical postoperative period when patients transition from hospital-based care to home recovery.

  • Shoulder Surgery Anesthesia
  • Upper Extremity Surgical Pain Control
  • Orthopedic Anesthesia Protocols

This therapeutic focus supports improved surgical outcomes by ensuring patients experience effective pain relief that facilitates early mobilization and rehabilitation following orthopedic interventions.

Alpha-2 Adrenergic Agonist Applications

The institution pursues targeted investigation of dexmedetomidine, an alpha-2 adrenergic receptor agonist, examining its role as a local anesthetic adjuvant in peripheral nerve blockade. Research explores the pharmacological mechanisms through which this agent extends the duration of sensory and motor blockade, contributing to the understanding of adjuvant-mediated prolongation of regional anesthetic effects.

  • Dexmedetomidine Dose Optimization
  • Perineural Pharmacology
  • Anesthetic Adjuvant Research

This work has implications for developing evidence-based guidelines for adjuvant dosing strategies that can be applied across various regional anesthesia applications, potentially improving clinical practice standards in pain medicine.

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Matched clinical trials

  • Study on Dexmedetomidine and Ropivacaine for Pain Relief in Shoulder Surgery Patients

    Not yet recruiting

    1 1 1
    Belgium
  • Study on the Effectiveness of Dexmedetomidine, Ropivacaine, and Dexamethasone for Pain Relief in Patients Undergoing Shoulder Surgery

    Not recruiting

    1 1 1
    Belgium