Digestive System Diseases
The gastroenterology department at Multiprofile Hospital For Active Treatment Hadji Dimitar OOD is conducting research on Crohn’s disease and hepatic encephalopathy, aiming to test new therapeutic options that can reduce disease activity and prevent hospital admissions.
- Rifaximin formulation to delay encephalopathy decompensation
- Subcutaneous RO7790121 for moderate to severe Crohn’s disease
These studies highlight the hospital’s dedication to improving outcomes for patients with digestive disorders in Sliven, Bulgaria.
Eye Diseases
In the ophthalmology scope, the site evaluates treatments for open-angle glaucoma and ocular hypertension, focusing on sustained‑release therapies that maintain intra‑ocular pressure control when standard eye drops are insufficient.
- Bimatoprost SR to extend IOP‑lowering effect
- Assessment of alternative delivery methods for glaucoma management
The research reflects a commitment to advancing vision‑preserving options for patients across the region.
Musculoskeletal Diseases
The department also addresses post‑menopausal osteoporosis, conducting comparative studies to determine whether new biologics can match the efficacy of established treatments in improving bone health.
- BP16 equivalence study with EU‑Prolia on bone mineral density
- Evaluation of serum bone turnover markers for therapeutic monitoring
This work underscores the hospital’s role in fostering innovative solutions for bone‑related conditions in the community.


