Bacterial Infections and Mycoses

At MUDr. David Zeman s.r.o. in Poruba, research in this area focuses on meningococcal infection and related vaccine studies. The trials are designed to assess immune response and safety, helping determine whether a new meningococcal ACYW conjugate vaccine performs as well as an established comparator in young children.

  • Study of meningococcal disease prevention in healthy infants and toddlers
  • Evaluation of antibody response to key meningococcal serogroups A, C, W, and Y
  • Assessment of vaccine effectiveness and overall safety in early childhood

This research supports better protection against serious bacterial infection through improved vaccination strategies for pediatric populations.

Virus Diseases

The site is also involved in clinical trials for varicella, with a strong emphasis on chickenpox vaccine research. These studies aim to confirm immune consistency across vaccine batches and compare a candidate varicella zoster virus vaccine with an existing vaccine, while also monitoring safety in healthy children.

  • Investigation of chickenpox prevention in healthy children aged 12 to 15 months
  • Measurement of immune response to varicella zoster virus after vaccination
  • Comparison of a new varicella vaccine with a standard option to support reliable protection

These trials help advance viral infection prevention by testing whether the investigational vaccine can deliver consistent and effective protection for young children.