Oncology & Hematologic Malignancies
At Lietuvos sveikatos mokslu universiteto ligonine Kauno klinikos, investigators are evaluating innovative treatments for a broad spectrum of cancers and blood disorders, with the goal of extending survival and preserving quality of life.
- Advanced melanoma and non‑small cell lung cancer
- Acute myeloid leukemia and myelodysplastic syndromes
- Prostate and bladder cancer
- Gastric and esophageal cancers
- Head and neck squamous cell carcinoma
- Renal cell carcinoma
- Myelofibrosis and other hematologic malignancies
These trials focus on testing targeted agents, immunotherapies, and combination regimens to assess safety and effectiveness.
Cardiovascular & Metabolic Disorders
Researchers conduct clinical trials on heart disease, hypertension, and metabolic conditions, aiming to lower cardiovascular risk and protect kidney function.
- Atherosclerotic cardiovascular disease and heart failure
- Chronic kidney disease with proteinuria
- Type 2 diabetes inadequately controlled
- LDL‑C and triglyceride‑lowering therapies
- Thromboembolic prevention after orthopedic surgery
- Cardiovascular outcomes with novel lipid‑lowering agents
The studies evaluate whether new medications can reduce heart attacks, strokes, or progression of renal impairment.
Autoimmune & Inflammatory Diseases
The department explores immune‑mediated conditions, seeking durable remission while minimizing adverse effects.
- Crohn’s disease and ulcerative colitis
- Rheumatoid arthritis and psoriatic arthritis
- Hidradenitis suppurativa and atopic dermatitis
- Systemic sclerosis and lupus nephritis
- Relapsing‑multiple sclerosis
- Immune thrombocytopenia and chronic urticaria
Trials often compare novel biologics or small molecules with standard care to determine efficacy and safety.
Neurology & Neurodegenerative Conditions
Clinical research targets disorders of the nervous system, focusing on disease‑modifying strategies and symptom control.
- Relapsing‑multiple sclerosis and secondary progressive MS
- Migraine prevention
- Neurogenic detrusor overactivity
- Neuro‑imaging biomarkers in MS
- Neuro‑inflammation in multiple sclerosis
- Neuro‑vascular complications after stroke
These studies assess long‑term safety of disease‑modifying therapies and their impact on disability progression.
Respiratory & Infectious Diseases
The site evaluates therapies for lung infections and chronic respiratory illnesses, aiming to reduce exacerbations and improve pulmonary function.
- Acute respiratory distress syndrome (ARDS)
- Chronic obstructive pulmonary disease (COPD)
- Community‑acquired pneumonia and COVID‑19
- Bronchiectasis
- Complicated urinary tract infections (as an infectious focus)
- Bacterial skin and soft‑tissue infections
Research includes antimicrobial agents and anti‑inflammatory drugs to shorten hospital stays and prevent complications.
Dermatology & Skin Disorders
Studies address both common and severe skin conditions, testing innovative biologics and small‑molecule inhibitors.
- Atopic dermatitis
- Chronic spontaneous urticaria
- Psoriasis and psoriatic arthritis
- Hidradenitis suppurativa
- Neovascular age‑related macular degeneration (ocular but related skin)
- Skin involvement in systemic diseases
The aim is to achieve rapid symptom relief and durable skin clearance with improved safety profiles.
Pediatric Growth & Endocrine Disorders
Research includes growth disorders in children, evaluating hormone therapies to support normal development.
- Short stature due to Turner syndrome or small for gestational age
- Growth hormone deficiency
- Acquired antithrombin deficiency affecting surgery
- Hormonal regulation in metabolic disease
- Bone health in chronic kidney disease
- Endocrine aspects of rare genetic syndromes
Trials compare weekly versus daily growth hormone regimens to determine optimal height velocity and safety.
