Pediatric Oncology and Hematology

Hospital Sant Joan De Deu Barcelona is active in pediatric oncology and hematology, with trials focused on cancers and blood disorders such as acute lymphoblastic leukemia, acute myeloid leukemia, neuroblastoma, sarcomas, and lymphomas. The research is centered on testing new treatments, improving survival, and refining care for children and young people with difficult-to-treat disease.

  • Acute lymphoblastic leukemia and acute myeloid leukemia studies aimed at improving treatment effectiveness and disease control
  • Neuroblastoma, solid tumors, and sarcoma research exploring new anti-cancer options
  • Hematologic malignancies trials evaluating better outcomes for relapsed or high-risk disease

This area reflects a strong focus on advancing pediatric cancer care through innovative therapies and better long-term outcomes.

Immunology, Inflammatory Disease, and Autoimmune Conditions

The site also conducts extensive research in immunology and autoimmune diseases, including atopic dermatitis, asthma, juvenile idiopathic arthritis, psoriasis, Crohn’s disease, and ulcerative colitis. These studies are generally designed to assess whether new therapies can reduce symptoms, improve disease control, and support better day-to-day functioning in children and adolescents.

  • Atopic dermatitis and asthma research evaluating symptom relief and treatment effectiveness
  • Inflammatory bowel disease studies in Crohn’s disease and ulcerative colitis
  • Rheumatology trials in juvenile idiopathic arthritis and related inflammatory disorders

This research helps broaden treatment choices for chronic immune-mediated conditions across the pediatric age range.

Neurology, Neurodevelopment, and Rare Genetic Disorders

A major part of the trial portfolio at Hospital Sant Joan De Deu Barcelona involves neurology, neurodevelopmental disorders, and rare genetic diseases. Research includes conditions such as spinal muscular atrophy, developmental and epileptic encephalopathies, autism spectrum disorders, Angelman syndrome, Rett syndrome, and Friedreich ataxia. The purpose is to evaluate new therapies and better understand how they may improve function, symptoms, and quality of life.

  • Spinal muscular atrophy and muscular weakness disorders research focused on functional improvement
  • Epilepsy and neurodevelopmental disorders studies examining seizure control and behavioral outcomes
  • Rare inherited neurological diseases investigating long-term treatment benefit and safety

These trials highlight a broad commitment to advancing care for children with complex neurological and developmental conditions.

Metabolic, Endocrine, and Growth Disorders

The research program includes studies in metabolic disease, endocrinology, and growth disorders, covering type 1 diabetes, obesity, short stature, growth hormone deficiency, Prader-Willi syndrome, and several inherited metabolic conditions. These trials are designed to test new treatments, support healthier growth and metabolism, and improve management of chronic conditions beginning in childhood.

  • Type 1 diabetes research focused on preserving insulin production and improving glycemic control
  • Growth disorders and short stature studies evaluating support for normal development
  • Inherited metabolic diseases trials assessing long-term safety and disease stabilization

The site’s work in this field reflects a strong interest in early intervention for lifelong metabolic and hormonal disorders.

Pulmonary, Cardiac, Renal, and Infectious Diseases

Clinical research at the site also spans respiratory disease, cardiology, nephrology, and infectious diseases. Trials include cystic fibrosis, asthma, cardiomyopathy, heart failure, chronic kidney disease, nephrotic syndrome, and infections such as sepsis and pneumonia. The main goal is to improve treatment effectiveness, reduce complications, and support better outcomes in children with serious medical conditions.

  • Cystic fibrosis and chronic respiratory disease studies evaluating long-term disease control
  • Kidney disease and proteinuria research aimed at slowing progression and improving renal health
  • Cardiac and infectious disease trials focused on safety, symptom reduction, and clinical recovery

This broad mix of studies shows the site’s involvement in both chronic disease management and acute care research.

Genetic, Rare Disease, and Advanced Therapy Research

The site has a strong profile in rare disease and advanced therapy research, including gene therapy, cell therapy, and other innovative approaches for inherited disorders. Trials involve Duchenne muscular dystrophy, hearing loss, mucopolysaccharidoses, hemophilia, osteogenesis imperfecta, and other rare genetic conditions. These studies aim to test new treatment strategies, assess safety over time, and improve outcomes where current options are limited.

  • Gene and cell therapy research for inherited and progressive childhood disorders
  • Muscular dystrophy, hemophilia, and rare metabolic diseases studies focused on disease modification
  • Genetic hearing loss and other rare conditions seeking better treatment options

This area underscores the site’s role in developing cutting-edge approaches for children with complex rare diseases.