Hospital Clinico San Carlos

Calle Del Profesor Martin Lagos Sn, Madrid, 28040, Spain

Neoplasms – Medical Oncology

The Medical Oncology department at Hospital Clinico San Carlos focuses on advanced research in neoplastic diseases, particularly targeting patients with EGFR‑mutant non‑small cell lung cancer who have progressed after standard EGFR‑TKI therapy.

Evaluating new combination regimens with immunotherapy and chemotherapy
Assessing overall survival benefits
Measuring progression‑free survival using standardized imaging criteria

These studies aim to improve treatment options for individuals with advanced lung cancer, offering hope for longer survival and better quality of life while reinforcing the site’s role as a leading non‑commercial research center in Europe.

Study of RSV vaccine immune response persistence and revaccination safety in adult lung and kidney transplant recipients

Recruiting

1 1 1
Investigated diseases:
- Respiratory syncytial virus infection
Investigated drugs:
- Respiratory Syncytial Virus, Glycoprotein F, Recombinant, Stabilised In The Pre-Fusion Conformation, Adjuvanted With As01E
Study of lurbinectedin and irinotecan in adults and young adults with advanced desmoplastic small round cell tumor

Recruiting

1 1 1
Investigated diseases:
- Desmoplastic small round cell tumour
Investigated drugs:
- Irinotecan Hydrochloride Trihydrate
- Lurbinectedin
Study of patritumab deruxtecan versus drug combination in patients with hormone receptor-positive, HER2-negative advanced or metastatic breast cancer

Recruiting

1 1 1 1
Investigated diseases:
- Hormone receptor positive breast cancer
Investigated drugs:
+1
Study of maridebart cafraglutide for patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Recruiting

1 1
Investigated drugs:
- Maridebart Cafraglutide
+12
Long-term safety study of eptinezumab given by intravenous infusion for children and adolescents aged 6-17 years with chronic or episodic migraine

Recruiting

1 1 1 1
Investigated drugs:
- Eptinezumab
A study of MK-1084 and pembrolizumab for patients with resected KRAS G12C-mutant non-small cell lung cancer

Recruiting

1 1 1
Investigated drugs:
A study of sacituzumab tirumotecan versus docetaxel, paclitaxel, or vinflunine for patients with pretreated advanced or metastatic bladder cancer

Recruiting

1 1 1 1
Investigated drugs:
+2
Phase 2 Study of Rinatabart Sesutecan with PEGFILGRASTIM in Adults with Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Recruiting

1 1 1
Investigated drugs:
- HUMAN IGG1 KAPPA MONOCLONAL ANTIBODY AGAINST FOLR1 CONJUGATED TO 1-[(2R,3R,4R,5S,52S)-1,2,3,4,5-PENTAHYDROXY-52-{[(2S)-1-{[(2S)-5-CARBAMOYLAMINO-1-OXO-1-{3-[({[(1S,9S)-9-ETHYL-5-FLUORO-9-HYDROXY-4-METHYL10,13-DIOXO-2,3,9,10,13,15-HEXAHYDRO-1H,12HBENZO[DE]PYRANO[3′,4′:6,7]INDOLIZINO[1,2-B]QUINOLIN-1-YL]CARBAMOYL}OXY)METHYL]ANILINO}PENTAN-2-YL]AMINO}-3-METHYL-1-OXOBUTAN-2-YL]CARBAMOYL}-7-[(2S,3R,4R,5R)-2,3,4,5,6-PENTAHYDROXYHEXYL]-46,54-DIOXO10,13,16,19,22,25,28,31,34,37,40,43-DODECAOXA-7,47,53-TRIAZANONAPENTACONTAN-59-YL]-2,5-DIOXOPYRROLIDIN-3-YL
+2
A study to evaluate the effectiveness and safety of vormatrigine in adults with focal epilepsy who are taking one to three anti-seizure medications.

Recruiting

1 1
Investigated drugs:
- VORMATRIGINE
Comparing Sotorasib and Pembrolizumab with chemotherapy for patients with advanced non-small cell lung cancer and a KRAS G12C mutation

Recruiting

1 1 1 1
Investigated drugs:
+11