Cardiovascular Disease Research

The Diabetologie department at Groupe Sos Sante is dedicated to advancing care for patients with Cardiovascular Diseases, including atherosclerotic disease, heart failure risk, and related outcomes in individuals with diabetes and obesity.

  • Evaluation of combination therapies aimed at lowering heart failure events and cardiovascular death
  • Assessment of novel GLP‑1 based agents for reducing major cardiovascular morbidity and mortality
  • Comparative safety analysis of tirzepatide versus dulaglutide on major adverse cardiovascular events
  • Investigation of cardiovascular benefits in overweight or obese patients with type 2 diabetes

The site’s investigators collaborate closely with local cardiology units to bring innovative treatment options to the community.

Metabolic and Obesity Research

Focused on Nutritional and Metabolic Diseases, the clinic conducts studies that target weight management, glycaemic control, and overall metabolic health in adults with type 2 diabetes and excess body weight.

  • Trials testing the efficacy of new agents for sustained weight loss in obesity
  • Evaluation of therapies that improve glycaemic outcomes while supporting weight reduction
  • Exploration of treatment strategies that address both diabetes and obesity concurrently
  • Research on lifestyle‑integrated approaches to enhance metabolic wellness

Located in Le Creusot, the centre leverages its hospital setting to provide comprehensive support for participants throughout the studies.

Integrated Cardiometabolic Studies

By bridging Cardiovascular and Metabolic research, Groupe Sos Sante investigates complex conditions such as chronic kidney disease and painful diabetic peripheral neuropathy that often accompany diabetes and obesity.

  • Examination of therapies that slow chronic kidney disease progression in diabetic patients
  • Assessment of novel compounds for reducing neuropathic pain in type 2 diabetes
  • Studies on surrogate markers linking metabolic health to cardiovascular outcomes
  • Integrated analyses of weight, kidney function, and heart failure risk

Four dedicated investigators lead these multidisciplinary projects, fostering collaboration across specialties to improve patient outcomes.